利用赤血鹽和電聚合薄膜來修飾電極的電化學感測器應用

Metal Hexacyanoferrate and Electro polymerized films modified electrode for electrochemical sensor Applications

Balamurugan deva(Balamurugan deva)

指導教授 ： 陳生明

國立臺北科技大學/工程學院/能源與光電材料外籍生專班研究所/博士(2014年)

https://doi.org/10.6841/NTUT.2014.00911

摘要

此篇論文主要著重在於利用電化學方法合成薄膜及金屬赤血鹽(MHCF)來偵測多種重要的生物分子,有毒物質和藥物. 用玻璃碳電極(GCE)來當作工作電極混合物。碳材料例如官能基化的多層奈米碳管(f-MWCNT)，石墨烯氧化物(GO)在所有論文中常被用來當作基材。鑭系的金屬例如鏑，釔和鐠常被用來合成赤血鹽。薑黃素和氨基酸則常被用來做電聚合使用。一個簡易的技術被用來合成金屬赤血鹽(MHCF)。 利用新興的電化學方法合成赤血鹽鏑(DyHCF)和官能基化多層奈米碳管(f-MWCNT)並利用此複合材料來同時偵測抗壞血酸(AA)，尿酸(UA)，和多巴胺(DA)。赤血鹽釔(YHCF)和官能基化多層奈米碳管(f-MWCNT)複合材料在茶葉樣品中則被用來當作兒茶素的感測器.而赤血鹽鐠(PrHCF) 飾電極也常用在亞硫酸鹽的氧化反應中。赤血鹽鐠(PrHCF)在不同條件下的型態在一開始被廣泛的研究。聚薑黃素修飾電極被用來同時偵測腎上腺素(EP) 和醋氨酚 (PA)。石墨烯氧化物(GO)和聚精氨酸共同修飾的電極被用來同時偵測丁螺環酮(buspirone)，異煙肼(isoniazid)，和吡嗪酰胺(pyrazinamide)藥物。所有被合成的材料都有經由X光繞射方法(XRD)，傅立葉轉換紅外光譜儀(FT-IR)，紫外線光譜儀(UV)，掃描式電子顯微鏡(SEM)，能量散佈分析儀(EDX)，X射線光電子光譜法來測定過性質。所有的電化學感測器都有經由真實的樣本分析去證實已具有感測器榜樣的水準. 此外所有被提出來的電化學感測器有好的線性範圍，低偵測極限，還有高靈敏度和穩定性這些優點。

關鍵字

電化學 ； 赤血鹽 ； 釔 ； 鏑 ； 鐠 ； 釔 ； 聚薑黃素 ； 聚精胺酸

並列摘要

This thesis study mainly focuses on the electrochemical synthesis of Metal hexacyanoferrate (MHCF) and Electropolymerization modified electrode for the determination of variety of important biomolecule, toxic materials and pharmaceutical drugs respectively. Glassy carbon electrode (GCE) has been used for working electrode fabrications. Carbon materials such as functionalized multi walled carbon nanotube (fMWCNT), Graphene oxide (GO) has been used as substrate materials for all studies. Rare earth metals such as Dysprosium, Yttrium and praseodymium have been used for synthesis of MHCF. Curcumin and amino acid arginine has been used for electropolymerization. A facile electrochemical technique has been employed for synthesis MHCF and polymerization. A novel composite of Dysprosium hexacyanoferrate (DyHCF) – fMWCNT has been fabricated for electrochemical simultaneous determination of Ascorbic Acid (AA), Uric acid (UA) and Dopamine (DA). Yttrium hexacyanoferrate (YHCF) – fMWCNT composite has been used for catechin (CA) sensor in tea samples. Praseodymium hexacyanoferrate (PrHCF) modified GCE has been used for sulfite oxidation. The morphological studies of PrHCF at different conditions have been studied for the first time. Poly Curcumin (poly CM) modified GCE has been prepared for simultaneous determination of epinephrine (EP) and paracetamol (PA). GO – poly arginine modified electrode has been prepared for the simultaneous electrochemical determination of buspirone, isoniazid and pyrazinamide drugs. All synthesized materials has been characterized using X-ray diffraction method (XRD), Fourier transform infra-red (FT-IR), Ultra violet (UV), Scanning electron microscopy (SEM), Energy-dispersive X-ray (EDX), X-ray photo electron spectroscopic method. All electrochemical sensor has been confirmed with corresponding real sample analysis to reach the prototype level sensor. Moreover all reported electrochemical sensors have the advantages of good linear range, low detection limit, good sensitivity and stability.

並列關鍵字

Electrochemical ； hexacyanoferrate ； Dysprosium ； praseodymium ； Yttrium ； poly Curcumin ； and poly-arginine

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