預防牙科相關感染之含銅生醫陶瓷體外抗菌影響

Antibacterial effect of bioceramic contained copper in prevention of dental-related infection in vitro

黃明燦(MIN-TSAN HUANG)

指導教授 ： 歐耿良

臺北醫學大學/口腔醫學院/醫療器材產業碩士專班/碩士(2013年)

https://doi.org/10.6831/TMU.2013.00116

摘要

無資料

關鍵字

氧化锆陶瓷材料 ； 抗菌 ； 生物膜 ； 銅離子

並列摘要

Synthesis of Cu-incorporated (0.5 wt.% Cu) bioceramic (Cu-ZrO2) was conducted in the present study. The bacterial strains, Gram-positive bacterial Staphylococcus aureus (S. aureus) ATCC6538P, and Gram-negative bacterial Escherichia coli (E. coli) ATCC8739 were used in the antibacterial test based on JIS Z2801:2010 specification. Antibacterial test demonstrated that the Cu-ZrO2 possessed the antibacterial properties against both Gram-positive bacterial S. aureus and Gram-negative bacterial E. coli, with an antibacterial rate of nearly 100%. It was found that the Cu+ ions can be released from the surface of the Cu-ZrO2 bioceramic then kill bacteria by destroying cell walls and cell membranes, causing their cytoplasm to run off and lose its duplication ability.

並列關鍵字

Zirconium oxide ； Antibacterial ； Biofilm ； Cu+ ion

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