含銅類鑽碳塗層電極對電燒刀熱損傷和組織沾黏之影響

Cu doped DLC coating electrode subatrate for electrosurgery thermal damage and tissue sticking effect

阮耀陞(YAU-SHENG RUAN)

指導教授 ： 陳玫秀

臺北醫學大學/口腔醫學院/醫療器材產業碩士專班/碩士(2013年)

https://doi.org/10.6831/TMU.2013.00127

摘要

電燒儀器使用時所引起煙霧、組織沾黏和熱損傷為電燒刀使用期間最重要的議題。以含銅類鑽碳塗層電極將產生較少的組織沾黏和血液貼附，同時熱損傷溫度也明顯低於未改質處理之電極。因此推估，含銅類鑽碳塗層電極也會較未改質處理之電極引起總量較小的熱損傷區、橫向熱損傷區、纖維組織區和擁有較快的組織恢復過程，透過Western blot分析發現其含銅類鑽碳塗層電極較未改質處理電極的組織出現較少的NF-κB, caspase-3和MMP-9等發炎反應。本研究表示含銅類鑽碳塗層處理將有效增進電燒刀系統使用時的表現。

關鍵字

電燒刀 ； 組織沾黏 ； 熱損傷 ； 含銅類鑽碳塗層

並列摘要

Surgical smoke, tissue sticking, and thermal injury are major concerns during electrosurgery. The Cu-DLC-electrodes generate a less amount of sticking tissues and adhesive blood cells. Thermography revealed the surgical temperature in liver tissue from the Cu-DLC-electrode was significantly lower than the SS-electrode. Moreover, Cu-DLC-electrodes caused a relatively smaller total injury area, lateral thermal injury area, fibrotic tissue area, and a faster remodeling process than the SS-electrodes. Western blot analysis showed that rats treated with Cu-DLC-electrode expressed lower levels of NF-κB, caspase-3, and MMP-9 than SS-electrode. This study reveals that the plating of Cu-DLC film on electrode improves the performance of electrosurgical unit.

並列關鍵字

electrosurgery ； tissue sticking ； thermal injury ； cupper-doted diamond-like carbon

參考文獻

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