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  • 學位論文

肥胖女性進行胃繞道與胃袖狀切除手術後 飲食攝取、身體組成與血液組成的變化

Dietary Intake, Body Composition and Blood Parameter Changes in Obese Women with Roux-en-Y Gastric Bypass and Sleeve Gastrectomy

指導教授 : 葉松鈴

摘要


本研究目的為探討肥胖女性進行胃繞道與胃袖狀切除手術後飲食攝取、身體組成與血液生化數值的變化。採病歷回溯法收集2012年1月1日~2014年12月31日於台北醫學大學附設醫院進行減重手術的病患 資料,篩選出7位RYGB與7位SG手術之病患,兩組在術前平均年齡、身體質量指數、飲食攝取與身體組成無顯著差異(p>0.05)。結果顯示,在手術後3-6個月期間,RYGB組體重流失率高於SG組(RYGB, 67.8% vs. SG, 44.1%, p<0.05) ; 每日熱量攝取量也顯著少於SG組(RYGB, 700 ± 241 kcal/day vs. SG, 1034 ± 256 kcal/day, p<0.05)。術後7-12個月兩組病患在熱量攝取、體重、腰圍、脂肪重顯著低於術前(p<0.05),營養素攝取量、身體組成與血液生化值兩組間無顯著差異(p>0.05)。在RYGB組中有6位第2型糖尿病患,術後7-12個月空腹血糖與HbA1C顯著低於術前(BS, 226.7 mg/dl to 135.5 mg/dl; HbA1C, 9.3% to 6.6%).。本篇研究顯示,RYGB 組因手術後食物攝取量與小腸吸收面積小於SG組,在術後短期內對體重、脂肪重減少具有顯著的效果 ; 但7-12月後RYGB組熱量攝取上升與SG組相近,因此兩組在身體組成與血液生化值無顯著差異。

並列摘要


This is a retrospective study to investigate the impacts of two different bariatric surgeries on dietary intake, body composition and biochemical parameters of obese women. Patients who were scheduled for Roux-en-Y Gastric Bypass (RYGB) and Sleeve Gastrectomy (SG) from January 1, 2012 to December 31, 2014 were enrolled in this study at Taipei Medical University Hospital. Seven patients performed RYGB operation and seven age- and body mass index (BMI)-matched patients underwent SG operation were recruited. There were no significant differences in dietary intake and body composition at baseline between the two groups (p>0.05). The results indicated that excess body weight loss percentage (%EBWL) was higher (RYGB, 67.8% vs. SG, 44.1%, p<0.05) whereas the calorie intake was lower in the RYGB group than the SG group (RYGB, 700 ± 241 kcal/day vs. SG, 1034 ± 256 kcal/day, p<0.05) at 3-6 months after surgery. Calorie intake and the body weight, waist circumference, fat mass were significantly reduced in both groups at postoperative 7-12 months. No significant differences in nutrient intake, body composition and biochemical parameters were observed at this time point. Six out of the 7 patients underwent RYGB surgery had type 2 diabetes mellitus. The fasting blood glucose (BS) levels and HbA1c were significantly reduced 7-12 months after surgery (BS, 226.7 mg/dl to 135.5 mg/dl; HbA1C, 9.3% to 6.6%). Because the food intake and intestinal absorption were lower in patients with RYGB operation than those of the SG patients, the reduction of weight and fat mass were much obvious at early phase after surgery. However, the calorie intake in the RYGB group rebound to the amount comparable to the SG group at 7-12 month and thus no differences in body composition and blood biochemical were found between RYGB and SG groups at this time point.

參考文獻


第七章 參考文獻
一、 英文參考文獻
Arnlov, J., Ingelsson, E., Sundstrom, J., & Lind, L. (2010). Impact of body mass index and the metabolic syndrome on the risk of cardiovascular disease and death in middleaged men. Circulation 121(2):230-236.
Ben-Porat, T., Elazary, R., Yuval, J. B., Wieder, A., Khalaileh, A., & Weiss, R. (2015). Nutritional deficiencies after sleeve gastrectomy: can they be predicted preoperatively? Surg Obes Relat Dis 11(5):1029-1036.
Benaiges, D., Flores-Le-Roux, J. A., Pedro-Botet, J., Ramon, J. M., Parri, A., Villatoro, M., et al. Goday, A. (2012). Impact of restrictive (sleeve gastrectomy) vs hybrid bariatric surgery (Roux-en-Y gastric bypass) on lipid profile. Obes Surg 22(8): 1268-1275.

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