以病人為導向的藥品適應症諮詢系統-以腸胃科用藥為例

民眾對於自身之用藥安全隨著資訊的發展，益顯關心。目前一般醫院均有在藥袋上提供列印用藥資訊，如適應症和注意事項等，但由於藥袋上的用藥資訊有限，且以一般性資訊為主，無法針對就醫民眾個別病情，提供客製化的用藥資訊。衛生署官方網站也有提供藥品適應症查詢，其內容雖然完整，但卻過多又難懂，病人很難確切知道自己服用的藥品與疾病的關係。本研究首先將衛生署藥品適應症內容，依據藥理分類對應到相關的疾病和症狀，分別建立疾病和症狀藥品適應症資料庫，其次再利用病人醫囑單所紀錄的疾病診斷及症狀，運用前項所建立之疾病和症狀藥品適應症資料庫的關聯性階層架構-醫療本體論，進而對應出該病人所服用藥品的適應症。如此產出的藥品適應症，係依據病人現有的疾病及(或)症狀，除了有切身的感受，容易了解之外，更讓病人因關連到自己的症狀及疾病，提醒正確的用藥資訊，提供病人多一重用藥安全的保障。

關鍵字

藥品適應症；腸胃科用藥；關聯性階層架構；醫療本體論；用藥安全

並列摘要

The public has shown great concerns on the drug safety along with the increasing accessibility of prescription drug information. Hospitals generally print this information on the medicinal package, such as indications and cautions. Due to the limited space on the package, most of them provide general defined conditions. However, patients’ condition may be different from one to another; unified information may not satisfy patient’s requirement regarding each individual situation. Although Department of Health has established an online drug indication query database system to the public. Nevertheless, the database is full of jargon which may increase difficulties for non-medical professionals to understand the implications between medication and sickness. Therefore, in the present study we started to categorize those enlisted drug indications from the official website based on pharmacological characters in relation to diseases and symptoms, to construct two respective databases and associated relationship hierarchy - Medical Ontology. Subsequently, we cross-referenced the medical orders for each patient and applied that information to the databases in order to relate drug indications with a patient's specific prescription. The indications thereby generated are made in accordance with a patient's ongoing symptoms and diagnosis. The medical ontology of the present study could help patients be more insightful on their own medical conditions and treatments, which concomitantly ensure drug safety.