探討番茄對於停經後婦女代謝症候群的影響

Effects of Tomato on Metabolic Syndrome in Postmenopausal Women

陳芊穎(Chien-yin Chen)

指導教授 ： 簡怡雯

臺北醫學大學/公共衛生暨營養學院/保健營養學研究所/碩士(2014年)

摘要

代謝症候群增加心血管疾病的罹患風險，研究指出攝食番茄可以降低心血管疾病的風險因子。停經婦女容易有腹部脂肪和內臟脂肪囤積，增加心血管疾病危險因子。本實驗為隨機開放式介入性試驗，探討以台灣特有種黑柿番茄（ASVEG Hualien No.20）對於停經後體重過重婦女代謝症候群的影響。實驗於2013年10起，在臺北醫學大學校園內進行。招募受試者後隨機分為芽菜組與番茄組，為期8週。每週進行體位測量、營養教育與諮詢課程。給予番茄組黑柿番茄，建議在早、午餐進食。提供綠豆芽菜給芽菜組，並限制攝食番茄和其製品。在第0、8週採血，進行血脂值與血糖等生化檢驗分析。共53人完成實驗，其中芽菜組23 人，番茄組30 人。結果得介入8週後，兩組的體重、身體質量指數、腰圍、臀圍和腰臀比皆顯著下降（p < 0.05）。番茄組在體重、體脂肪重、體脂百分比、腰圍和臀圍下降幅度皆顯著於芽菜組。相較於芽菜組，番茄組有更顯著的降低血清中總膽固醇、三酸甘油酯、收縮壓和血糖，並有效增加血清抗氧化力和類胡蘿蔔素濃度。因此，番茄能有效的改善體重過重的停經婦女的代謝症候群危險因子。

關鍵字

停經婦女 ； 番茄 ； 體脂 ； 血脂 ； 抗氧化生物標記

並列摘要

According to 2005-2008 Nutrition and Health Survey in Taiwan （NAHSIT） the prevalence of metabolic syndrome is 57.3% in postmenopausal women. Metabolic syndrome is one of the risk factor of cardiovascular disease （CVD）. Postmenopausal women likely to have abdominal fat and visceral fat accumulation, abnormal lipid profile, increased CVD risk factors. Epidemiological studies suggest that consumption of tomato-based food might reduce the CVD risk. The aim of this study was to assess whether the consumption of tomato affects the risk factors of metabolic syndrome. We conduct a 8-week open-label, randomized controlled dietary intervention trial. Subjects were recruited from Taipei Medical University in October 2013, were randomly assigned into 2 groups, asked to consume a control （sprouts） diet and a tomato diet. Blood samples were collected at baseline and 8th week and were analyzed for lipid profile, blood sugar, antioxidant biomarkers-ferric reducing ability of plasma （FRAP） and serum carotenoids. Blood pressure, body weight, and body fat were also measured every week. After the 8 weeks dietary intervention, body weight, body mass index, waist circumference, hip circumference （p < 0.05） were significantly decreased in both group. Moreover, tomato group was significantly decreased on body weight and body fat mass, body fat percentage, waist circumference, hip circumference than control group. Tomato group was significantly decreased on serum total cholesterol, triglyceride, systolic blood pressure and blood sugar, and increased on high-density lipoprotein cholesterol, but not in control group. Antioxidant biomarkers-FRAP, beta-carotenoids and lycopene were significantly increased in tomato group, also not in control group. Therefore, tomato could reduce the risks of metabolic syndrome in postmenopausal women.

並列關鍵字

postmenopausal women ； tomato ； body fat ； blood lipids ； antioxidant biomarkers

參考文獻

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