In this study, We Performed two groups of sound wave experiment to compare the measurement flux between acupuncture point (acupoint) and non-acupuncture point on hand skin. We build an external mechanical to stimulate on hand by sound wave. We observe the effect of microcirculatory with two different beating frequencies: (A) 1 times the HR. (B) 1.5 times the HR on hand. The experiment results show that the average LDF flux on acupoint is significantly increased than on the non-acupoint in group A, with p is smaller than 0.05 by paired t-test on acupoint, and without significantly increased in group B. If implies that, this mechanism could be used to improve the microcirculatory of hand.