This study examines the factors that influence the decision-making of institutional investors in their ETF investment. The results show that the ETF holdings of institutional investors are significantly negatively related to the size of ETFs and positively related to expense ratios, indicating that institutional investors invest in small-size ETFs for high returns. This study also examines whether “smart money” effect documented by Gruber (1996) and Zheng (1999) reflect ETF selection ability of institutional investors. The results show that institutional investors as a whole could not predict ETF performance. Neither could different types of institutional investors are able to predict future ETF performance and invest accordingly.