鈣磷系親水基齒科復型材料-齒科複合樹脂的研發

Investigation of Dental Composite Resins with Smart Restorative Function and Hydrophilic Property

吳蕙妤(Hui-Yu Wu)

指導教授 ： 陳弘森

共同指導教授 ： 陳文正(Wen-Cheng Chen)

高雄醫學大學/口腔醫學院/口腔衛生科學研究所碩士班/碩士(2013年)

摘要

本研究以二鈣磷酸鹽粉末作為強化光聚合高分子樹脂基質材的強化分散相(dispersed phase)，希望藉由鈣磷酸鹽填料的特性複合一新型牙科樹脂，藉以改善目前牙科臨床上遭遇的二次齲齒(secondary caries)及填補失敗(restoration fracture)的問題。實驗於二鈣磷酸鹽表面做不同的表處處理，並將合成後的樹脂試片將進行一系列的物理化學分析與顯微結構的觀察。研究結果發現，N表面處理能增強抗壓強度及彈性係數，讓樹脂之材料性質較偏向脆性材質；而S組的包覆處理，則會降低彈性係數，讓材料性質較偏向韌性材料。此外，兩種表面處理皆有的組別相對於其他組別擁有較好的機械強度。離子釋放能力的分析部份，A組擁有最好的離子釋放能力。其餘組別依序排列為B > C > D。而雖然D組的離子釋放能力雖然較差，但相對來說也代表填料粒子較不容易水解且能減緩降解的過程。經本研究發現有N表面處理和S組的包覆處理之鈣磷酸鹽類牙科樹脂確實能夠增加的樹脂的強度，且也能夠擁有鈣、磷離子的釋放潛能，相信在未來在臨床使用上是具有發展及應用的空間。

關鍵字

牙科複合樹脂 ； 鈣磷酸鹽 ； 鈣磷離子釋放

並列摘要

The study is to characterize the composites of the dicalcium phosphate anhydrous (DCPA) particle as fillers for dental resin ,and to improve the problems of secondary caries and restorative fracture. Fillers were fabricated with different surface treatment on the surfaces of DCPA particles. The complete samples were investigated the physicochemical properties and microscopic structures. Results showed the sample largely releases the calcium and phosphorus ions in the solution after immersed 24hrs and thermal cycling. In mechanical analysis, we found the particles with N-surface modification would increase reinforcement significantly. Moreover, the S-treated would increase the toughness of the material, and would form the good bonding strength between the resin matrix and fillers. In the results of ions release ability found the A group was the best ions release ability, and followed B and C group. The D group was the worst ions release ability. However, the ions release ability of D group is the poorest, it could slow degradation process. This study find could increase the compressive strength and have the potential of release of calcium and phosphate ions by N-treated and S-treated DCPA resin calcium phosphate composite resin. In future, we believe it will have a good development and application in clinic.

並列關鍵字

Dental composite resin ； Calcium phosphate ； ions releasing ability

參考文獻

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