南台灣病人之口腔與顎顏面病灶回溯性研究

Retrospective Study of Oral and Maxillofacial Lesions in Patients from Southern Taiwan

李浩正(Hao-Jheng Li)

指導教授 ： 何坤炎

高雄醫學大學/口腔醫學院/牙醫學研究所/碩士(2014年)

https://doi.org/10.6832/KMU.2014.00148

摘要

目的
本研究目的提供南台灣有關一般、兒童以及老人之口腔與顎顏面切片病灶之資料。

材料與方法
於2000-2011年在高雄醫學大學附屬中和醫院口腔病理科具有年齡、性別以及組織學診斷記錄的口腔顎面病灶均被納入本研究中。根據年齡，共分成一般(0-99歲)、兒童(0-15歲)及老人(>60歲)三組。病灶主要分成四大類：腫瘤卅類腫瘤反應病灶、囊腫卅偽囊腫、發炎卅感染病灶以及其他各類病灶。

結果
1.在一般病患中總共有紀錄37210個診斷(20992人，23061個病灶)。大部份病灶是腫瘤卅類腫瘤反應病灶，其次為發炎卅感染病灶、其他各類病灶、及囊腫卅偽囊腫病灶。最多為鱗狀細胞癌，並且是最常出現之惡性病灶。
2.在兒童病患中共有848個診斷(780人，819個病灶)。最多是出現在發炎卅感染病灶，其次為腫瘤卅類腫瘤反應病灶、囊腫卅偽囊腫病灶及其他卅各類病灶。粘液囊腫為最常出現之病灶，其次為齒瘤及含牙囊腫，兩者加總為所有兒童病灶之41% 。
3.在老人族群中共有6726個診斷(4461人，4953個病灶)。大多數病灶是發炎卅感染，其次是腫瘤卅類腫瘤反應病灶。鱗狀細胞癌是最常出現之病灶。另外，有高比例出現癌前期病灶。

總結
本研究與其他國家研究具相似之傾向結果，但某些詳細數據有差別，其可能原因為不同之標準和區域環境因素所產生。值得注意的是鱗狀細胞癌和癌前期病灶佔一般及老人病患之口腔顎面病灶之大部份。

關鍵字

口腔病灶 ； 口腔保健 ； 流行病學 ； 鱗狀細胞癌

並列摘要

PURPOSE
This study aimed to provide updated information on biopsied oral and maxillofacial (OMF) lesions in the general, pediatric and geriatric population from southern Taiwan.

MATERIALS & METHODS
OMF cases (2000–2011) from the patients containing records of age, sex, and histological diagnoses were retrieved from the Oral Pathology Department of our institution. Our cohort was categorized as 0–99 years, 0–15 years, and >60 years respectively for the general, pediatric and geriatric patients. These lesions were classified into four main categories: tumor/tumor-like reactive lesions, cystic/pseudocystic lesions, inflammatory/infective lesions, and others/miscellaneous lesions.

RESULTS
1.A total of 37,210 OMF diagnoses (20992 patients, 23061 lesions) were included in the category of general patients. Most of these lesions were distributed in the group of tumor/tumor-like reactive lesions, followed by the groups of inflammatory/infective lesions, cystic/pseudocystic lesions, and others/miscellaneous lesions. Squamous cell carcinoma was the most common OMF lesion, and was also the most frequent malignant lesion.
2.A number of 848 OMF diagnoses (780 patients, 819 lesions) were recorded in the pediatric patients. Most lesions were in the inflammatory/infective group, followed by the groups of tumor/tumor-like lesions, cystic/pseudocystic lesions and others/miscellaneous lesions. Mucocele was the most common lesion, followed by odontoma and dentigerous cyst, which comprised 41% of total numbers of pediatric biopsied lesions.
3.A total of 6,726 diagnoses (4461 patients, 4953 lesions) were collected from OMF lesions in the geriatric patients. Most of these lesions were distributed in the inflammatory/infective group, followed by tumor/tumor-like reactive lesions. Squamous cell carcinoma was the most common lesion, and, additionally, there was a high frequency of oral potentially malignant disorders.

CONCLUSION
The present study showed trends consistent to previous reports from other countries; however, some detailed information differed, perhaps due to the different criteria and different geographic distribution. It was worthy of note that squamous cell carcinoma and oral potentially malignant disorders comprised high percentages of general and geriatric OMF lesions.

並列關鍵字

Oral lesions ； oral health ； epidemiology ； squamous cell carcinoma

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