2-Phenylbenzothiazole是已知具有生物活性的天然物,其衍生物也在乳癌細胞、結腸癌細胞、卵巢癌細胞、腎臟癌細胞都有良好的活性。而點擊化學經常應用於藥物方面的研發,也是一種快速又有效率的一種合成方法。在本論文利用苯炔點擊化學來進行合成抗癌試劑。
2-Phenylbenzothiazoles are known natural products with biological activity. The derivatives are potential anti-cancer activity inter breast、colon、ovarian and renal cell. The click chemistry applications are in the drug discovery, and also fast and practical synthetic method In this study, we use the aryne click chemistry to design and synthesis anti-human agent