This report will show how to integrate set-design with human-space interactions in drama. By analyzing characters and background of Jean-Claude Carrière’s《L'Aide-Mémoire》, I tried to arrange the stage to reflect on characters’ tensions such as the contrast between male and female characters. In the beginning, the male character had control over the whole space but at the end, he left alone and female character, who seemed to gain power, occupied the space. By analyzing text, we could know how set-design could reflect on the transition of characters’ power structure. Therefore, I arranged my set-design through the method of space and interior design. By doing so, actor and actress, with the help of space/environment, could be more immersed in the characters and plot.