Business is very important for the economic growth of every country. The most successful economies have been boosted by growth in the business sector in all industries. There have been mergers and acquisitions and an enormous growth in entrepreneurship in all the successful economies of the developed countries. The developing countries are also following this trend in order to succeed in the global arena. With all these business ventures going on, it is equally important to make sure that the business is carried out in a way that will benefit all stakeholders. But in some instances, the business venture fails because of circumstances beyond their control. The main objective of bankruptcy prediction is early detection of decline in business activity, whether that decline is caused by factors within the company or outside. Prior studies highlight the most important factors (i.e., financial ratios) to be considered. However, most of them concentrate on the comparison of different statistical or data mining techniques at a single time point by using annual data. This study has addressed the longitudinal analysis of quarterly financial data on bankruptcy prediction. Using 210 companies listed in the Taiwan Stock Exchange (including 105 bankrupt and 105 solvent companies), our empirical results show that the predicting timings closer to the occurrence of actual events will lead to higher effectiveness on bankruptcy prediction. Specifically, prediction made at one or two quarters prior to bankruptcy generally has highest accuracy, precision, and recall rates. In addition, SVM outperforms J48 in the target prediction task. Finally, the inclusion of ratio-change variables has no positive effects on the effectiveness of bankruptcy prediction. Keywords: Bankruptcy prediction, Data mining, Decision tree induction, Support vector machines (SVM)