At present, the domestic industries of flat panel liquid crystal display have grown up rapidly, and the quality of LCDs becomes more and more important when there are a lot of LCDs around our lives. A critical factor of LCD panel quality is“Mura”. It is the un-uniform phenomenon in LCD panels. Traditionally, the quality of LCD panels is detected by human eyes, but it is subjective without any common criterion. In the recent years, an automation Mura inspection system has been developed by TTLA (Taiwan TFT LCD Association), which can calculate the attributes of Mura defects quickly to make the inspection process efficient and to make the judgment consistently. In addition, evaluating the ranks of Mura is always subjective, and serious disagreements and controversy may arise between LCD manufacturers and customers. There is lacking of Mura classification system in the present automation Mura inspection system. Although the serious degree of Mura defects was presented by JND values (Mura quality criterion), multiple JNDs in this vision model were defined as the comparison ratio of the Mura contrast (C) to the “one contrast threshold” according to SEMI (2002). However, some literatures reporting a non-linear relationship between contrast and multiple JNDs in human visual performance, so it is not uniformly to apply JND values in this vision model to establish the Mura rank standards from 1 to 3, 3 to 5……etc. Therefore, the experiment was designed in this research to obtain fitting functions of multiple JNDs for six typical Mura types. From the experimental result, non-linear functions were obtained, and then, the transformed function was found to modify original vision model. Finally, Mura ranking standard and Mura classification system were developed to be a standard communication platform for customers and suppliers.