異核鈀鈷雙金屬錯合物催化氨基磺酸酯分子內烯類氮丙啶化反應

Intramolecular Aziridination of Sulfamate Esters Catalyzed by Heterobimetallic Palladium-Cobalt Tetraacetate

李建旻(Jian-Min Li)

指導教授 ： 莊敬

中原大學/理學院/化學研究所/碩士(2013年)

https://doi.org/10.6840/cycu201300843

摘要

本論文我們採用異核雙金屬PdCo(OAc)4為催化劑進行分子內碳-碳π鍵的氮烯插入反應。本研究先以一級醇或二級醇合成allyl sulfamate和homoallyl sulfamate類起始物，並以PdCo(OAc)4為催化劑進行反應測試，除了得到預期的雙環氮丙啶化合物，還獲得經由醋酸開環的5員環和7員環化合物。在反應條件最佳化測試中發現在反應過程中沒有添加氧化鎂的狀態下對於產率沒有影響，PdCo(OAc)4會因醋酸鈀的廠牌不同，造成碳-碳π鍵的氮烯插入反應產率有明顯的不同，
而雙環氮丙啶化合物會隨著反應時間的增加逐漸轉換為醋酸開環產物。

關鍵字

鈀鈷雙金屬錯合物 ； 氮丙啶

並列摘要

In this research, heterobimetallic palladium-cobalt acetate was used as catalyst for the intramolecular carbon - carbon π bond nitrene insertion reaction. Allyl and homoallyl alcohols were used as starting material to synthesis allyl sulfamate and homoallyl sulfamate. PdCo(OAc)4 was found capable of catalyzing the nitrene insertion and the desired bicyclic aziridine compounds were obtained. Five and seven-membered ring compounds were also observed via ring opening of the aziridines by acetate. During the optimization of the reaction conditions, PdCo(OAc)4 made from different brands of palladium acetate, resulted different yield in the catalyzed aziridination reaction.

並列關鍵字

palladium-cobalt tetraacetate ； aaziridination

參考文獻

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