攜帶式及移動式氣相層析質譜儀建置毒化物檢量線

Establishing Calibration Curves of Toxic Substances on Portable and Mobile Gas Chromatographs/Mass Spectrometers

文儀婷(Yi-Ting Wen)

指導教授 ： 葉華光

中原大學/理學院/化學研究所/碩士(2018年)

https://doi.org/10.6840/cycu201800442

摘要

現今化學災害事故頻傳，國人的生命財產安全、環境都處於威脅的狀態中，快速分析、應變就顯得極為重要。藉由檢量線的建置，以利應變部隊在毒化物災害現場快速檢測，獲得現場濃度，以作為災情分析最佳工具，減低對人員及環境的危害性。
本研究主要以英福康攜帶式氣相層析質譜儀與德國布魯克移動式E2M氣相層析質譜儀進行毒化物之檢量線製備，以作為災情分析最佳工具，並分析比較兩者間的差異性。毒化物之選擇以桃園四大工業區申請毒化物較多的物質作為實驗藥品，包含了三氯甲烷、二甲基甲醯胺、1,4-二氧陸圜及吡啶等四種毒化物。
由實驗結果得知，採用攜帶式氣相層析質譜儀於三氯甲烷、1,4-二氧陸圜以及吡啶的線性回歸值R2皆有在0.95以上，檢量線建置成果可信度高，可提供各部隊作為定量分析之依據；二甲基甲醯胺的檢測結果線性回歸值R2僅有0.7512，二甲基甲醯胺屬於低揮發性物質，需要在高溫、高壓環境下才易揮發，因此，室溫下無法有效分析。
E2M氣相層析質譜儀對於四種毒化物檢量線建置線性回歸值R2除三氯甲烷為0.6321外，其餘三種樣品皆在0.1以下，定量分析結果可性度較低；但對於毒化物進行個別及四種混合的定性分析，皆可有效分析。
不論是何種裝備，每一台裝備都有限制條件在，因此應該搭配多種機器同時分析，以利在短時間內做出最佳的判斷，提供指揮官下達任務決心。

關鍵字

攜帶式氣相層析質譜儀 ； E2M氣相層析質譜儀 ； 三氯甲烷 ； 二甲基甲醯胺 ； 1,4-二氧陸圜 ； 吡啶

並列摘要

With the advancement of technology and the quality of living environment has increased. The number of chemical substances used in our country keeps increasing and it also contains many toxic chemicals. The operation of chemical substances has potential dangers such as leakage, fire, explosion, and terrorist attacks, and it not only makes the incidence of chemical scourge in our nation continue to rise but also may have a major impact on human health and the environment. Therefore, it is extremely important to rescue and restore the accident scene. Consequently, it is urgent for chemical accidents to confirm the type, concentration, and other unknown chemical reactions of hazardous materials in a short period of time so that rescue workers can quickly determine the way to deal with the disaster. Therefore, the precision and accuracy of the detection equipment at the accident site are important.
In this study, we used portable gas chromatography mass spectrometer （Portable GC-MS） and E2M to perform the poison preparation of the calibration curve and compared the differences between two were analyzed. The selection of poisons was based on the substances with the highest number of poisons applied as experimental drugs in the four major industrial zones of Taoyuan, including chloroform, dimethylformamide ,1,4-dioxane, and pyridine. The greatest superiority of both is the convenience of mobility which can help the rescue workers not to be restricted by the terrain and entrance the accident site for analysis.
It is hoped that through the construction of the calibration curve can help emergency response forces make quickly detect, inquiry application and serve as the best tool for disaster analysis to reduce the hazards of rescue workers and the environment.

並列關鍵字

Portable GC-MS ； E2M ； Chloroform ； N,N-Dimethyl formamide ； 1,4-dioxane ； Pyridine

參考文獻

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二、中文文獻：