- 學位論文
高頻電刺激下人體皮膚水份的變化量
Accessing the aquiferous content using high frequency eletrical impedance analysis
摘要
人體皮膚下包含許多複雜的組織，像是肌肉、脂肪等等，每個組 織的功用也不同，在皮膚下的組織中，皮膚下及內層的肌肉、脂肪在 短時間內並不會改變組成，短時間會產生改變的只有皮膚下組織的含 水量，因此、短時間內連續觀察皮膚下及其淺層組織的含水量變化可 以了解身體生理代謝健康情況。 本論文論述開發一個以現場可程式化晶片（FPGA）為核心之系 統針對人體皮膚注入高頻定電流訊號，能同時監控和紀錄人體的生物 阻抗生醫訊號，其所得之訊號可以在系統中儲存和即時顯示，也可以 透過USB通訊傳輸介面把生理訊號傳至電腦，所得之生理資訊，經由 Borland C++ Builder編輯視窗化軟體應用介面程式，顯示系統平台和 分析結果。 本研究目前所分析之資料分別為飲水前、飲水後、進食前、進食 後這四種類型，證明不同生理狀況含水量是有影響的。由於人體皮膚 在不同頻率下會得到不同的阻抗，利用高頻掃頻的方式找出特徵值的 範圍，並且利用觀察患有糖尿病患者之血糖代謝生物阻抗特徵值所產 生之皮膚下淺層組織水分變化探討皮膚水分和血糖變化的關係。
並列摘要
Under human skin, it is a complex tissue which consists of muscles, fat, and many more with different physiological states. However, the muscle and fat under the skin do not change in a short period of time except the aquiferous content inside and under the skin. Therefore, we will know the metabolism state of human being by observing the change of aquiferous content in superficial tissues under the skin in a short period of time. The FPGA programmable system chip was specifically designed to stimulate the body using constant current high frequency signal. In this way, the system has the ability to monitor and record biological impedance signals of body. The prototype system was also including functions of data display with LCD, data storage with FLASH memory, data communication with USB. An off-line PC window program was also provided for reviewing the recorded impedance and analyzed impedance with high frequency. The system was used to access the psychophysic effect of aquiferous content monitoring over four circumstances. They were situations of monitoring the before drinking water, after drinking water, before meal, and after meal. It was to examine the impact of aquiferous content on different physiological states. During different frequency stimulation, the impedance of skin changed, so we used high-frequency scan to find the range of frequency. And, we also observed the changes of aquiferous content of shallow tissue under human skin in patients with diabetes. The relationship between changes in the aquiferous content of the skin and in blood glucose was to be discussed.