Situation semantics is a new semantic theory generated in 1980s. The basic idea of this theory is that in thought and action we use complexes of objects and properties to directly and indirectly classify parts and aspects of reality, or situations. And, situation semantics is a theory of meaning based on that meaning is located in the interaction of living things and their environment. In both computer science and information science, an ontology is a data model that represents a set of concepts within a domain and the relationships between those concepts. Ontologies are used in artificial intelligence, the semantic web, software engineering, biomedical informatics and information architecture as a form of knowledge representation about the world or some part of it. In this paper, we will design the infomation system with infon in situation semantics. And, we will good use of the characteristic of entities, attributes and relations in ontology that is adopted to build the Knowledge storage structure.