- 學位論文
親水性奈米層狀鋯磷衍生物之製備 與其應用於環氧複材之性質 與牛血清蛋白吸附行為之研究
Synthesis and Characterization of Hydrophilic Layered Zirconium Phosphonate Derivatives for the Application of Epoxy Nanocomposites and Adsorption Behavior of Bovine Serum Albumin
摘要
人工合成無機/有機奈米混成層狀材料能依照應用上的需求，改變分子組成、視徑比與離子交換當量的分子設計後，使其表面的官能基多樣化且具有高的反應性，有利於添加入高分子單體中製備出奈米級複合材料，在熱性質與機械性質等皆有很好的效果。本研究以ZrOCl2・8H2O 與Vinylphosphonic acid ( VPA )反應，在 pH值為8 的反應條件下進行單一步驟有機/無機奈米混成合成反應，得到粒徑大小( particle size )為奈米尺度的晶相，其層間碳與碳鍵結形成共軛雙鍵( C=C-C=C- )的官能基。將具有奈米層級的人工合成鋯磷衍生物添加於牛血清蛋白質中，探討其吸附的行為，此種吸附行為能有利於在生物醫學上的應用，例如:蛋白質純化技術的開發或生物感測器等。另一方面也可應用於製備奈米級複合材料上，當做一種補強試劑，加入特定高分子單體( 環氧樹脂，Epon-828 )後，使人工合成層狀材料能均勻分散在基質裡，製備有機/無機奈米複合材料，由於人工合成磷酸鋯衍生物之層狀材料具有剛性的結構特性，能有效提升化學與物理性質，並藉由XRD、FT-IR、EA、ICP-AES、TGA、DSC與TEM等儀器來加以鑑定結構並探討比較各種性質及其應用性。
並列摘要
Recently, polymer layered silicate nanocomposites (PLSNs) have been received much attention due to their potential for enhanced physical, chemical and mechanical properties compared to conventionally filled composites. The study of artificial layered organic/inorganic hybrid materials as a component for the preparation of nanocomposites is of current interest. The advantage of this artificial layered material is that the functional group, aspect ratio and particle size can be controlled by varying reaction condition compared to naturally occurring layered materials according to the purpose of use. Particle size and aspect ratio is very much important to achieve tunable physical and mechanical properties of the polymer. Zirconium phosphate/phosphonate is one of the artificial layered materials which are very much similar to clay minerals. We have prepared a new type of zirconium phosphonate derivatives (Zr-P) with the functional group of ~C=C-C=C at pH 8 in a single step reaction by hydrothermal process. It has high ion exchange capacity and the particle size of this material is in the nano order range. The structure of Zr-P compound has been characterized by XRD, FT-IR, EA, ICP-AES, TGA and solid state 31P-NMR. Presence of organic functional groups into the layers increase the compatibility between the polymer matrices. We have applied zirconium phosphonate derivatives (Zr-P) to prepare Epoxy/Zr-P nanocomposite. It has been observed that the physical and mechanical properties of this nanocomposite are improved a lot. The nanocomposite materials have been characterized by XRD, TGA, DSC and TEM etc. Protein (Bovine Serum Albumin, BSA) adsorption behavior of Zirconium phosphate nano-particles have also been investigated by UV-Visible spectroscopy which can be applied as biosensor.