應用於電流式電化學感測器之系統設計與實現

System Design and Implementation for Amperometric Electrochemical Sensor

朱政宏(Cheng-Hung Chu)

指導教授 ： 鍾文耀

中原大學/工學院/電子工程研究所/碩士(2011年)

https://doi.org/10.6840/cycu201100877

摘要

本研究係以電化學感測方法為基礎結合後端電流式讀出電路所設計實現一具多參數電化學感測系統，前端電化學感測部份，已成功備製以網版印刷為基板之酒精(乙醇)生物感測器，並使用商用血糖及尿酸感測電極搭配後端由本實驗室所開發之專利新型電流式讀出電路與微控制器(MCU)，透過PCB設計與佈局實現一具多參數電化學感測系統。

實驗結果顯示本系統所量測得網印酒精(乙醇)感測電極，於待測濃度範圍200~400 mg/dL，可獲得線性度99.78%，感測靈敏度為3.36 nA/(mg/dL)；血糖感測電極，於待測濃度範圍50~400 mg/dL，可獲得線性度98.50%，感測靈敏度為11.82 μA/(mg/dL)；尿酸感測電極，於待測濃度範圍2.6~20.4 mg/dL，可獲得線性度98.77%，感測靈敏度為5.34 μA/(mg/dL)，本系統適用於人體生理參數監測(血糖、尿酸)，網印拋棄式乙醇生物感測器，具有快速檢測酒精濃度之能力，可應用於食品工業及酒駕檢測。

關鍵字

電化學感測 ； 電流式讀出電路 ； 微控制器 ； 酒精(乙醇)生物感測器

並列摘要

This research is based on Electrochemical Sensor method with the backend amperometric readout circuit for sensing a variety of parameters with system design and implementation. Front-end part of the electrochemical sensing, an amperometric alcohol (ethanol) biosensor based on screen printed carbon electrodes (SPCEs), were successfully developed in this research. Also, using the commercial blood sugar and uric acid sensing electrodes as the backend, developed by the laboratory’s patented with new current-mode readout circuit and microcontroller (MCU), through the PCB design and layout to implement an electrochemical sensing with multi-parameter system.

Experimental results show that the system is measured by the screen printed carbon electrodes alcohol (ethanol), glucose sensing electrodes, and uric acid sensing electrode. In printed carbon electrodes alcohol (ethanol), the measurement concentration ranges 200~400 mg/dL, obtain linearity of 99.78%,sensor sensitivity of 3.36 nA /(mg/dL). In glucose sensing electrodes, the measurement concentration ranges 50~400 mg/dL, 98.50% linearity, the sensor sensitivity 11.82 μA /(mg/dL). In uric acid sensing electrode, the measurement concentration ranges 2.6~20.4 mg/dL, 98.77% linearity, the sensor sensitivity 5.34 μA/(mg/dL). This system is applicable for monitoring human physiological parameters (such as blood glucose, uric acid), screen printing disposable ethanol biosensor, which has an ability for rapid detection of alcohol concentration, can be used in the food industry and drunk driving test.

並列關鍵字

Current-Mode Readout Circuit ； Alcohol (Ethanol) Biosensor ； Microcontroller ； Electrochemical Sensing

參考文獻

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