以MSP430建構肺音聽診量測裝置

Develop a lung sound auscultation measurement device using MSP430 Chip

吳俊毅(Wu-Chun Yi)

指導教授 ： 徐良育

中原大學/工學院/生物醫學工程研究所/碩士(2012年)

https://doi.org/10.6840/cycu201200127

摘要

聽診器是目前醫師最常用來檢測心肺聲音與判斷肺部疾病的裝置。它具有非侵入式、便宜等優點，但在聽診時無法記錄與保存肺音資訊。而且能偵測的疾病受到人耳聽覺能力所限制。同時，目前市面上肺音相關儀器開發並不普及，且沒有統一的規範準則。所以，無法提供醫療人員全面的肺音資訊。
因此，本研究的目的在於發展一套可儲存傳輸的肺音量測系統，以輔助專業醫療人員在診斷上的參考與決策。本研究使用自製肺音量測裝置來進行肺音訊號波形的量測，並使用MSP430F149微處理晶片進行數位化處理與周邊控制。不但能夠進一步對肺音資訊做儲存與參數分析，並能提供教學上或醫生診斷上的一個參考依據，達成監控肺音量測資訊之目的。
本系統測試結果顯示，系統頻率響應範圍在20Hz~2KHz;肺音量測無論在正常肺音或異常肺音的驗證也與先前文獻所得到的肺音特徵相似。因此，證明本研究成功建構出一套肺音量測系統。然而，本系統仍有待臨床上的驗證，分析實際的病患，以驗證本系統在輔助醫生診斷疾病的能力。
關鍵字:聽診法(auscultation)、異常肺音(adventitious sounds)。

關鍵字

異常肺音 ； 聽診法

並列摘要

Stethoscope is the most commonly used device by the physician to detect heart and lung sounds and diagnosis lung disease. Its advantage is non-invasive and cheap. But it cannot record and save information about lung sounds during auscultation. Additionally, the disease detection capability is limited by the hearing ability of the user. Moreover, the development of lung sounds instrument on the market is not very popular. And, there is no standard guidelines. Thus, it cannot provide complete lung sound information to the medical personnel.

For this reason, the purpose of this study is to develop a lung sound measurements system that can store and transmit lung sound to assist the professional medical personnel in diagnosis or reference. This research constructed lung sound measure device for lung sound signal measurement and used MSP430F149 microprocessor chip for waveform digitization, signal processing and peripheral control. The proposed system can not only analysis and storage information of lung sound parameters but also provided a reference for teaching or medical diagnosis in order to achieve the goal of lung sound information monitoring. The purpose of this research is achieved monitor lung sound measurement information.

The test results show that frequency response of the system is in the range of 20Hz ~ 2KHz. Validation measurement of either normal and abnormal lung sounds illustrate characteristics that are similar to previous literature. Therefore, this demonstrates that this research constructed a lung sound measurement system successfully. However, this system need to be clinically verified by analyzing actual patients in order to demonstrate the capability of the system in , assisting doctors in disease diagnose.
Key Words: auscultation、adventitious sounds.

並列關鍵字

adventitious sounds ； auscultation

參考文獻

[5] J. F. Murray; J. A. , “Textbook of respiratory medicine,” Philadelphia: W. B. Saunders, 1994.

[8] H. Pasterkamp, S. Kraman, and G. Wodicka “Respiratory sound-advance beyond the stethoscope,” Am. J. Respir. Crit. Care Med., vol. 156. pp. 974-987, 1997.

[9] F. Dalmay, M. T. Antonini, P. Marquet, R. Menier, “Acoustic properties of the normal chest,” Eur, Respir, Vol. 8, pp.1761-1769, 1995.

[10] A. Sameer, P. K. Yasemin, “Design of a DSP-based instrument for real-time classification of pulmonary sounds,” Computers in Biology and Medicine ,Vol.38, Issue 1, pp. 53-61 ,January 2008 .

[12] A. Kandaswamy, C. Sathish Kumar, Rm. Pl. Ramanathan, S. Jayaraman, N. Malmurugan, “Neural classification of lung sounds using wavelet coefficients,” Computers in Biology and Medicine 34,523-537, 2004.