常壓電漿製備酸鹼敏感與抗生物沾黏薄膜之研究

Study on preparation of pH sensitive and Anti-biofouling Membranes by Atmospheric-Pressure Plasma

許馨勻(Xin-Yun Xu)

指導教授 ： 魏大欽

中原大學/工學院/化學工程研究所/碩士(2012年)

https://doi.org/10.6840/cycu201200648

摘要

本研究以常壓輝光介電質放電對聚偏二氟乙烯同時進行表面活化與接枝步驟，使膜材接枝丙烯酸以具有酸鹼敏感性質，隨後再於酸鹼敏感膜材上接枝甲基丙烯酸聚乙二醇酯，使其兼具抗生物沾黏之效果，探討單體濃度、改質時間對於接枝效能的影響。電漿處理後的膜材利用水接觸角、全反射式傅立葉轉換紅外線光譜儀、掃描式電子顯微鏡、X射線光電子能譜儀等儀器分析表面化學與物理結構，再進行水通量測試探討膜材酸鹼敏感性質，並利用蛋白質吸附實驗及細菌貼附測試了解膜材抗生物沾黏之效果。
　　研究發現在常壓輝光介電質放電功率為100 W，改質時間為60 s的電漿參數下製備之PVDF-g-PAA改質膜材，經由XPS分析所得之鍵結比例接近於理論PAA之鍵結比例，顯示電漿改質對於單體結構的破壞並不強烈。且藉由調整適當的單體濃度，使PVDF-g-PAA接枝密度約為0.274 mg/cm2，可於水通量測試中呈現最佳酸鹼敏感性質。於PVDF-g-PAA膜材上接枝第二層單體甲基丙烯酸聚乙二醇酯，單體濃度30 wt%之接枝密度大於10 wt%，而改質時間30 s之單體結構保有度優於60 s，由水通量測試與蛋白質吸附測試可得知(PVDF-g-PAA)-g-PPEGMA同時具有酸鹼敏感性質與抗生物沾黏效能，其BSA移除率高達約90 %，且有效降低Escherichia coli及Staphylococcus epidermidis細菌貼附。
　　本研究所開發的常壓輝光介電質放電可以快速、乾淨、均勻的製備酸鹼敏感性與抗生物沾黏膜材，除此之外也可運用在其他單體的接枝方面，是一種極有潛力的技術。

關鍵字

酸鹼敏感膜材 ； 抗生物沾黏膜材 ； 常壓電漿

並列摘要

This study utilized atmospheric dielectric barrier discharge (DBD) plasma to graft poly(acrylic acid) (PAA) and poly(Ethylene Glycol) methacrylate (PEGMA) onto poly(vinylidene fluoride) (PVDF) membranes. The chemical structure, surface morphology of the surface-modified PVDF membranes were characterized by fourier transform infrared attenuated total reflectance (FTIR-ATR), electron spectroscopy for chemical analysis (ESCA), scanning electron microscopy (SEM) and contact angle. In addition, the water permeability and the protein adsorption of the grafted membranes were studied.
　　It was found that the grafting density of PVDF-g-PAA membranes can be controlled via different monomer concentrations. According to the ESCA results, the bonding ratio of the grafted PAA is close to the theoretical value, which shows the plasma treatment could retain most of the monomer’s molecular structure. After grafting, the water flux of PVDF-g-PAA membranes decreases significantly with the increase in pH value of test solution because the carboxyl group varied from neutral to charged state which changes the chain configurations.
　　(PVDF-g-PAA)-g-PPEGMA membranes incubated under monomer concentration of 30wt% were found to have a higher grafting density than that of 10wt%. Furthermore, the ESCA results show that the retention of monomer’s molecular structure at the grafting time 30s is better than grafting time 60s. (PVDF-g-PAA)-g-PPEGMA membranes exhibit both pH sensitivity and anti-biofouling property. The BSA removal percentage of (PVDF-g-PAA)-g-PPEGMA membranes is about 90%. In addition, the bacteria attachment test shows that the resulting membranes could reduce the attachment of Escherichia coli and Staphylococcus epidermidis effectively.

並列關鍵字

DBD glow discharge ； pH sensitive membrane ； anti-biofouling membrane

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