摘要
人體心臟進行週期性的運動促成血液在血管內流動，血液的流動使得血管壁進行擴張與否，此時因心臟的運動使血管內產生的壓力稱為血壓(Blood Pressure, BP)，心臟運動的週期所產生的壓力曲線則稱為血壓波形。影響血壓與血壓波形的條件，如：血管阻抗性、血管適應性、血液輸出量、心臟跳動頻率等各種生理因素，這些皆是影響血管壓力與波形的原因。 根據心臟血管文獻討論指出，正確且精準的量測上臂動脈處，其壓力及波形可得到較正確的中心動脈壓及波形，本研究以流體力學理論以及管道內之力學的部份進行研究，定義出心率、阻抗、流量、壓力之間的關係，建構一套類似於人體血壓的流體壓力系統，調整這四個參數後呈現出不同的壓力波形，並分析流體壓力系統與人體血壓波形之間的關係。 將本研究製作出的流體壓力系統，藉由調變系統上之參數，如：心率、阻抗、流速以及血壓，進而模擬出類似於人體血壓之波形。其驗證部份是藉由Spacelabs、OMRON、日規三款電子血壓計對本系統進行量測。整體來說，三款電子血壓計在量測上皆有不同值之差異，而且在數據分析的部份不論是收縮壓、舒張壓以及心率與本流體壓力系統的統計分析上有顯著差異(P<0.0001)。 因此，藉由本研究所開發的流體壓力系統，調變本系統之參數進而產生各種型態之壓力波形，以便了解人體心血管循環系統之作用機制，用以提供未來對於心血管系統研究上的幫助。
並列摘要
The human heart is undergoing periodical movement to maintain blood flow in the blood vessels. The dilatation of the blood vessel is caused by the circulation of blood, and the pressure in the blood vessels caused by the pumping of the heart is called blood pressure (BP). When the heart’s pumping periodically, it creates a pressure wave called blood pressure waveform. Affect the conditions of blood pressure waveform, such as: impedance, compliance, stroke volume, heart rate, etc. Affect the reasons of blood vessels pressure waveform. According to the cardiovascular paper discussesd, description measure upper arm artery of exact, can be receives more correct the aortic pressure waveform. In this study, hydrodynamics theory and the pipe flow’s part to research, define to the relationship between heart rate, impedance, flow, pressure. Construct a similar to human blood pressure of blood pressure simulation system. Regulate these four parameters showing different from pressure waveform, and analysis the relationship between the blood pressure simulation system and the human blood pressure. In this study, construct to blood pressure simulation system through to regulate these parameters such as: heart rate, impedance, flow and pressure, then similar to human blood pressure. The Spacelabs, OMRON and Japan product non-invasive electronic sphygmomanometer to blood pressure simulation system of test and verify part. Over all, the three non-invasive electronic sphygmomanometer measure differences between in different. Whether the systolic, diastolic and heart rate with blood pressure simulation system is meaningfully for the statistical analysis. Therefore, through to blood pressure simulation system, regulate to these parameters, then showing of each type’s waveform and the mechanism of action of realize to cardiovascular circulatory system. Provide help on the research of the cardiovascular system.