探討心導管手術後導致肺癌、皮膚癌、乳癌、甲狀腺癌、大腸癌、中風之發生率

根據衛生署統計，癌症高居國人十大死因的榜首，但就死亡人數而言，第二位的心臟疾病、第三位的腦血管疾病、第四位的糖尿病和第十位的高血壓性疾病的病人總和，遠超過罹癌人數，顯示心血管疾病亦是危害國人健康的主要殺手；且根據統計，每年平均約有二萬二千名心臟心血管疾病患者須接受心導管手術治療來保住性命。而我們想探討的是，手術過程中所置入的放射性物質經過血管後，是否會在體內產生影響，甚至發生病變，且手術次數越多，是否病變發生率會越高，另外也討論慢性病患者(糖尿病、高血壓) 動心導管手術是否會增加罹癌或中風的機率。之後我們使用卡方檢定、趨勢檢定、羅吉斯迴歸以顯著水準a= 0.05下分析後，發現心導管手術過程中的放射線物質，並不會影響肺癌、皮膚癌、乳癌、甲狀腺癌、大腸癌、中風的發生率，若有發生得情況，可能是因為其他因素而造成，而非心導管手術所致。

關鍵字

心導管手術；皮膚癌；肺癌；乳癌；中風；大腸癌；甲狀腺癌；卡方檢定；費雪精準性檢定；趨勢檢定； logistic regression

並列摘要

According to the statistics from Ministry of Health and Welfare, cancer ranks first in the ten leading causes of death in Taiwan. However, in terms of numbers of deaths, the combined death toll of heart disease which ranks second, cerebrovascular disease which ranks third, diabetes which ranks fourth and hypertension which ranks tenth is far more than the numbers of deaths of cancer, indicating cardiovascular disease is the major causes of death in Taiwan. Besides, the statistics shows that more than 22,000 patients suffer from cardiovascular disease retain their lives by cardiac catheterization. The focus of our interests are whether the radioactive material put in during surgery will have impact to the body or even cause disease; whether the probability of disease causing by surgery increases with the numbers of surgeries applied. Besides, we are also interested in whether cardiac catheterization increases the probability of getting cancer or a stroke among chronic patients (diabetes, hypertension). Carrying out analysis using Pearson’s chi-squared test, trend test, and logistic regression at significant standard a=0.05, we found that the radioactive material used in cardiac catheterization will have no impact on the probability of getting lung cancer, skin cancer, breast cancer, thyroid cancer, colorectal cancer and stroke. In case of the occurrence of above-mentioned disease, it arises from other factors rather than cardiac catheterization.

並列關鍵字

stroke ； trend test ； skin cancer ； Pearson's chi-squared test ； Fisher's exact test ； thyroid cancer ； colorectal cancer ； lung cancer ； breast cancer ； logistic regression ； cardiac catheterization