整合電穿孔及自動光功率控制電路於生醫之應用

Integration of Electroporation and Automatic Photo-Power Control Circuit for Biomedical Applications

林庭臣(Ting-Chen Lin)

指導教授 ： 程德勝

國立暨南國際大學/科技學院/電機工程學系/碩士(2015年)

摘要

目前將藥物傳遞至組織及血液的方式為經消化器官傳遞及注射給藥。此種治療方法會使病患產生不舒適感及無法針對患部做直接的處理，另外藥物也可能使患部以外的區域產生藥物過敏。而電穿孔的技術越趨成熟，但市面上的儀器都有攜帶不方便、昂貴的缺點。
　　本論文為設計高電壓電穿孔電路以及自動光功率控制電路，以電穿孔電路達到無痛式經皮膚直接給予患部治療，並同時以雷射控制角質層的撥離或移除，促進給藥進行的效率。並以微處理器同時控制，使此電路系統具備可程式化、體積小、低耗費的趨勢。
　　本論文之高電壓電路將電壓由30V及2A的輸入電壓、電流，到輸出電壓從30V ~ 300V，再利用高壓脈波切換電路將電壓轉換為脈衝電壓的形式，作為一非侵入式電穿孔儀器。而光功率控制的電路則是使發光二極體自動在環境溫度從-20˚C ~ 60˚C穩定輸出的光功率，以作為任何需要穩定光功率之光電儀器的基礎。

關鍵字

電穿孔 ； 自動光功率控制 ； 直流升壓切換式電路

並列摘要

At present, the way of drug delivery is mainly by oral and injection. Such treatments make patients feel discomfort and are unable to deliver to the treatment area directly. Although electroporation technique becomes mature, the instruments still have the disadvantage of non-portable and expensive.
The aim of this study was to design an electroporation circuit combined with automatic photo power control system to achieve the purpose of painless therapy and drug deliver directly to the treatment area. With the help of microprocessor, the system is able to control two circuits simultaneously, making the system programmable, small size, and low-cost.
In this study, the high-voltage circuit can boost from an input voltage of 30V and current of 2A to the output voltage of 30V~300V, and can convert to form a voltage pulse by the pulse conversion circuit. The photo power control circuit is used to maintain the output photo power of light-emitting diodes at ambient temperatures from -20˚C ~ 60˚C automatically.

並列關鍵字

Electroporation ； DC-DC ； photo power control

參考文獻

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