功能性奈米顆粒在毛細管電泳上的分離探討

本篇論文討論關於功能性奈米螢光顆粒( Functional fluorescent particles )的製備並結合毛細管電泳( Capillary Electrochromatography )，基於不同大小分離的探討研究。在製備螢光顆粒部分，採用溶膠-凝膠( Sol-Gel )方法包覆螢光染料，最後採用粒徑分析儀 ( Photon Correlation Spectroscopy ；PCS )、原子力顯微鏡( Atomic Force Microscope；AFM )、傅立葉轉換紅外線光譜儀；FT-IR )、多功能光譜儀鑑定。本研究成功製備60 nm、120 nm、225 nm、500 nm、1000 nm，二氧化矽螢光顆粒，並且比單純染料有更好的螢光穩定性。接下來探討用毛細管電泳分離5 種大小R6G@SiO2和接上官能機後用毛細管電泳分離的可行性，最後看是否可以就由分離的結果求得未知體積的R6G@SiO2 大小。

關鍵字

毛細管電泳；奈米顆粒

並列摘要

This study I synthesize the several size fluorescent silica nonaparticles and determine which size use photon correlation spectroscopy (PCS) , atomic force microscopy . Then analyze fluorescent silica nonaparticles used the fourier transform infrared instruments and fluorescent spectroscopy . Capillary electrophoresis with laser-induced fluorescence detection was used to individually detect 60, 120, 225, 500 and 1000 nonameter fluorescent silica and individually measure their electrophoretic mobility. We can determine which size fluorescent silica is analyzed by Capillary electrophoresis. Using the correlation between electrophoretic mobility and the particles size can known which size the fluorescent silica is.