An efficient cascade protocol between malononitrile, benzylidenemalononitrile, and (E)-tert-butyl-3-benzylidene-2-oxoindoline-1-carboxylate has been developed. Fully substituted spirocyclic oxindole derivative bear two all-carbon quaternary centers. The reaction proceeds through a Michael/Michael/1,2-addition reaction. The spirocyclic oxindole derivatives were obtained in reasonable-to-good chemical yields (45 - 81 %) and high levels of diastereoselectivities (14:1 - >20:1 d.r.) using a catalytic amount of commercially available TMEDA (30 mol%) in ACN at 0 ℃ for 8 - 20 h.