Abstract This paper is the use of optical frustration total reflection method with excitation surface plasma wave gallium Arsenide Otto configuration and Kretschmann configuration, as well as Gallium ortho Otto configuration and Kretschmann configuration, surface plasma wave measurement of amyl chloride. In addition, the simulation of this paper mainly research program software, Matlab software. We use Matlab software to write the program of the total reflection coefficient of three layers of media. To run computer simulations and map the surface plasma wave spectrum. For the research results of this paper, please refer to 5.1 Conclusions in Chapter 5