Twin screw rotor compressor has the advantages of simple structure, unique system, and reliable and easy operation; therefore it is widely used in various construction works involving aerodynamics and refrigeration air conditioning, etc., making it a new compressor model with a broad application future. This study intends to determine the three key precision parts of screw compressors by making an in-depth research into the assembly process of the twin screw rotor compressor and the size design of various parts. By utilizing and analyzing the results obtained from the 1-D and 2-D assembly simulation software developed to analyze the assembly process, possible situations and the defective rate that may occur after assembly was obtained. Modification advice was therefore proposed based on the original design and size, in order to improve the yield rate of the twin screw rotor compressor, reduce any difficulties in assembly, and cut down on both labor cost and time, while providing future designers with some reference for shortening the design period.