高血壓性腦出血病患不同年齡間死亡率之雙峰分佈

Bimodal distribution of age on the mortality of hypertensive intracerebral hemorrhage

謝嘉如(Jia-lu Shei)

指導教授 ： 洪炯宗

國立中央大學/資訊電機學院/資訊工程學系/碩士(2012年)

摘要

腦中風為突然而劇烈的局部性神經機能障礙，並持續24小時以上或導致死亡。根據世界衛生組織所公布數據資料顯示，腦中風為世界第三大死因(僅次於癌症及缺血性心臟病)，其中顱內出血造成的死亡率更高於其他型中風，例如：蜘蛛網膜下腔出血、腦栓塞等。臨床資料亦顯示出不論是出血型中風抑或是缺血型中風，高血壓皆為最主要的獨立危險因子。在台灣，有許多關於顱內出血死亡率的研究，但尚未有僅針對高血壓型顱內出血病患，在包含年輕族群的不同年齡間各項統計分析研究。根據以上理由，我們的研究會著重於以下幾點：1. 高血壓型顱內出血病患不同年齡間個數分布的情形。 2. 高血壓型顱內出血病患不同年齡間，死亡率分布的情形。 3. 造成高血壓型顱內出血病患的獨立危險因子。

關鍵字

高血壓 ； 腦出血 ； 死亡率

並列摘要

Stroke is defined as a sudden and severe focal neurological deficit lasting more than 24 hours or leading to death. According to the World Health Organization report, stroke is the third leading cause of death worldwide (after cancer and ischemic heart disease), and intracerebral hemorrhage occupiers higher mortality rate than subarachnoid hemorrhage, ischemic stroke, and other kind of strokes. Clinical data shows that whether hemorrhage strokes or ischemic strokes, hypertension is the most dominant risk factor. There are many investigations of mortality rate of intracerebral hemorrhage in Taiwan, but there is no statistical analysis about the age including the younger and hypertension-associated intracerebral hemorrhage patients. For the reasons mentioned above, our research focuses on following points: first, the distribution of numbers in different age groups of hypertension-associated intracerebral hemorrhage patients; second, the distribution of mortality rates in different age groups of hypertension-associated intracerebral hemorrhage patients; third, the cause of independent risk factors of hypertension-associated intracerebral hemorrhage.

並列關鍵字

mortality ； hypertension ； intracerebral hemorrhage

參考文獻

Hanley DF. “Spontaneous intracerebral hemorrhage”, N Engl

Hanley DF et al. “Spontaneous intracerebral hemorrhage”,

for intracerebral hemorrhage in the young are

“Hypertensive intracerebral hemorrhage in young people:

J Med, 344: 1450–60, 2001