光體積變化描記器量測人體末梢血管體積變化與血管硬化之關係

本研究是建立一套光體積變化描記器訊號量測系統，進行PPG訊號分析。探討目的有二，第一部份探討PPG內部隱藏訊號與生理現象關聯性，第二部分探討PPG訊號與血管硬化之關係。在本研究中PPG原始訊號經由EMD訊號處理拆解出多個特徵訊號，再經由FFT訊號處理，透過頻譜圖可發現心率及呼吸的頻率訊號。由此結果得知，PPG原始訊號經由EMD訊號處理後，可成功在特徵訊號中找到呼吸的生理訊號。本系統針對單一手指頭進行動脈脈波訊號量測，得到血管硬化（SI）及血管反射（RI）兩項參數指標。藉由SI與RI兩項指標與已應用於臨床診斷之動脈硬化篩檢儀所檢測之hfPWV及ABI兩項參數指標進行相關度比較。實驗結果顯示，此四項指標中SI與hfPWV統計相關係數高達0.862。本研究建立的PPG訊號量測系統，藉由實驗得知，本系統與動脈硬化篩檢儀具有高相關度，故本系統可作為動脈硬化先期檢測工具。

關鍵字

光體積變化描記器；血管硬化；經驗模態分解

並列摘要

The research was to set up a signal measuring system, which can precede the analysis of Photoplethysmography(PPG) signal. There were two purposes for the research applying the system. First was to study the correlation between the internal concealed signal of the PPG and the physiological phenomenon. Second was to study the relation between the PPG signal and the atherosclerosis. In the study, the primitive PPG signal was split to several characteristic signals through the Empirical Mode Decomposition(EMD) , then the method of the Fast Fourier Transform was applied to acquire spectrum which can find the signal relating to the heartbeat and the respiration frequency. According to the experiment result, the physiological phenomenon of respiration was successfully found from the characteristic signals which were, through EMD, transferred from the primitive PPG signal. Meanwhile, the Stiffness Index (SI) and the Reflection Index (RI) of atherosclerosis could be found by the measurement of the artery pulse signal collected by the single-finger detection. Compared to the hfPWV and the ABI which are using for the clinical diagnosis on atherosclerosis, the experiment result showed the SI strong correlating to the hfPWV by statistical factor 0.862. The study demonstrated the PPG signal measurement system had strong correlation with hfPWV which is applied for clinical diagnosis on atherosclerosis. So, the system can be for the early stage check tool to diagnose atherosclerosis.

並列關鍵字

Photoplethysmography ； Empirical Mode Decomposition ； Atherosclerosis

參考文獻

12. 陳昱廷，2007，三通道血液容積波擷取系統之研製，碩士論文，國立台北科技大學，自動化科技研究所，台北。

2. A. C. Burton, 1939, “The range and variability of the blood flow in the human fingers and the vasomotor regulation by body temperature,” American Physiological Society, vol.127, pp. 437-453.

3. Alison L. Lee, Albert J. Tahmoush, J. Richard Jennings, 1975, “An LED-Transistor Photoplethysmograph,” IEEE Transactions on Biomedical Engineering, vol. BME-22, pp. 248-250.

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光體積變化描記器量測人體末梢血管體積變化與血管硬化之關係

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