The locally twisted cube LTQn is a variation of the hypercube Qn, and the diameter of LTQn is only about half of the diameter of Qn. For interconnection, some efficient communication algorithms can be designed based on the ring structure. In addition, two edge-disjoint Hamiltonian cycles also provide the edge-fault tolerant Hamiltonicity for the interconnection network. Hung [Theoretical Computer Science 412, 4747–4753, 2011] designed an O(n2n) time algorithm to construct two edge-disjoint Hamiltonian cycles in LTQn. In this thesis, we provide parallel algorithms for each vertex in LTQn to determine which two edges were adopted in the first or second Hamiltonian cycles, respectively. By connecting these edges, we can construct two edge-disjoint Hamiltonian cycles in LTQn where n ≥ 4.