以米根黴生產L型乳酸

Production of L (+)lactic acid by Rhizopus oryzae

林怡君(I-Chun Lin)

指導教授 ： 許垤棊

大同大學/工程學院/生物工程學系所/碩士(2004年)

摘要

L型乳酸,分子式C3H6O3,為含有氫氧基的有機酸,是生物的代謝中間產物。L型乳酸可以在動物和人類細胞中新陳代謝因為這些細胞含有L型乳酸去氫酵素。L型乳酸還可用於生産L型乳酸聚合物。L型乳酸聚合物屬於無毒的高分子化合物,具有生物相容性,可用於製造生物可分解的塑膠、纖維以及生醫材料等。本研究以黴菌Rhizopus oryzae CCRC 9363為L型乳酸生產菌,針對生物反應器的種類與最適操作條件來進行探討。最後由實驗得知以改良型的生物反應器為最適生產L型乳酸的反應器。

關鍵字

生物反應器 ； L型乳酸 ； 米根黴

並列摘要

L-lactic acid, C3H6O3, an organic acid with hydroxy group is a metabolic intermediate in living organisms. Only the L-form of lactic acid is metabolized in animal and human cells. This is due to the fact that only L-lactate dehydrogenase is synthesised by these cells. L-lactic acid can be polymerized to form Polylactic acid (PLA). L-form PLA is a nonvirulent macromolecular compound with biocompatibility, which used in the manufacture of new biodegradable plastics, fiber, and biomedical material. This experiment used fungus, Rhizopus oryzae CCRC 9363 to produce L-lactic acid and discussed the types of bioreactor and best conditions. Final, it is discovered that the modified bioreactor is the best bioreactor to produce L-lactic acid.

並列關鍵字

bioreactor ； L-lactic acid ； Rhizopus oryzae

參考文獻

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