含奈米銀之複合水膠材料製備及性質研究

摘要 Part 1 本研究首先將AgNO3與1-vinyl-2-pyrrolidinone(VP)單體螯合成VP-Ag+錯化合物，再利用UV光照射使得VP上的CN提供一個電子給Ag離子還原成具有奈米級(66.4 nm)的銀粒子，再依不同比例之濃度添加於N-isopropylacrylamide(NIPAAm)製備成一系列奈米複合水膠，探討在不同濃度下之膨潤度、交聯時間、膠體抗菌能力、溫度對膨潤度的變化及機械性質。結果顯示，奈米複合水膠之膨潤度隨著奈米銀添加量之增加而上升，而添加量之增加也讓膠體有好的抗菌效果並促進膠體的交聯時間，機械強度亦隨著奈米銀添加量之增加而有下降的趨勢。摘要 PART 2 本研究之目的為明明膠(Gelatin)添加不同濃度比的奈米銀粒子，製成一系列不同濃度之奈米複合之水膠，更進一步的使用戊二醛(Glutaraldehyte, GA)進行化學交聯而形成很強的結構，並討論添加奈米銀粒子後，對明膠膨潤行為、機械性質抑菌效果作一研究探討。

關鍵字

水膠；奈米銀； VP ； NIPAAm ；明膠；複合材料

並列摘要

ABSTRACT Part 1 This study firstly used AgNO3 and 1-vinyl-2-pyrrolidinone(VP) to monomer cheated VP-Ag+ complex, them ultraviolet irradiation was used to let CN group in 1-vinyl-2-pyrrolidinone(VP) donored an electron for silver ion. That makes silverion to reduce a silver nanosize particles and the mean silver particle size is below 66.4 nm. The different concentration ratio of silver nanoparticles were added into N-isopropylacrylamide (NIPAAm) system to prepare a series of nanocomposite hydrogels. The influence of the content of silver nanoparticles on the equilibrium swelling ratio, mechanical property, crosslinking reaction rate, antibacterial be havior and was investigated in this study. Results showed that the swelling ratio and crosslinking reaction rate for the present composite gels increase with the increase of incorporation of silver nanoparticle into the N-isopropylacrylamide (NIPAAm) hydrogels, but crosslinking density and shear modulus (G) do not increase with an increase of the content of silver Nanoparticles. Finally, bacterial inactivation effect and crosslinking reaction rate of NIPAAm/silver nanocomposite gels increased with an increase silver nanoparticles concentration. PART 2 The objective of the study is to explain the effect of the different concentration ratio of silver nanoparticles added into gelatin on the various properties of the gelatin hydrogel. Hence, a series of silver nanocomposite hydrogels were prepared. The hybrid hydrogels were further crosslinked with chemical crosslinking agent such as glutaraldehyte (GA) to form very strong structure. The influence of the content of silver nanocomposite into hydrogels on the equilibrium swelling ratio, mechanical properties, inhibition bacterial and different temperature swelling ratio was investigated in this study

並列關鍵字

Hydrogels ； VP ； Silver ； Nanoparticles ； NIPAAm ； Gelatin

參考文獻

1. Hoffman, A. S. J Control Release 1987, 6, 297.

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3. Hirokawa, E.; Tanaka, T. J Chem Phys 1984, 81, 6379.

4. Ricka, J.; Tanaka, T. Macromolecules 1984, 17, 2916.

5. Eisenberg, S. R.; Grodzinski, A. J. J Membr Sci 1984, 19, 173.

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含奈米銀之複合水膠材料製備及性質研究

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