於CD片上設計與製作被動式微混合器

DESIGN AND FABRICATION OF PASSIVE MICROMIXER ON CD PLATE

王毅軍(Yi-Chun Wang)

指導教授 ： 簡昭珩

大同大學/工程學院/機械工程學系所/碩士(2009年)

摘要

由於晶片型實驗室所扮演的角色地位日趨重要，各種相關生醫分析所需的元件，如微幫浦、微致動器、微流道、微混合器等的相關研究也逐日成長，而其中一項重要的研究課題就是微混合器的設計。一般微混合器的功能是提供給生物晶片或是晶片型實驗室的前處理，若是能有效的促進微混合器的混合效率，不但能使整個系統的工作效率增加，同時系統的尺寸也就能隨著縮小。
本研究為利用價格低廉且容易取得之CD片配合本實驗室已建構之MEMS製程技術，設計並利用熱壓成型技術製作混合器(Mixer)於CD式晶片，可降低底材與操作成本及穩定品質，以達成本研究之目標。主要研究以離心力原理以及實驗測試進行混合器的微流道設計，最後以PDMS封閉流道，再予以離心驅動力，即進行最後的混合測試。
經實驗證實，使用熱壓成型方式在製作流道上雖有幾何形狀上之限制，但最終所設計之混合器確實達到製作於CD片上之目的，且經色度分析以及酸鹼度分析量測，證實在驅動轉速為2500rpm且時間為20秒之情況下，本混合器確實達到混合之效果。

關鍵字

混合器 ； 生物晶片 ； 微機電技術 ； 熱壓技術

並列摘要

MEMS technology have been developed and applied in various kinds of fields, such as, optics, power, sensor, bioengineer and etc. However, with the improvement of quality of the life, people want to have better medical treatment. MEMS technology is applied by biotechnology such as PCR chip, detection chip, separated chip and etc. Effective and rapid mixing is essential to microfluidic systems. In this paper, MEMS technologies and hot embossing process are used to fabricate the micormixer on CD plate.
In this research, CD is choose to be the base for passive micromixer constructed on, and fabricated by hot embossing technology. It can reduce the substrate cost, operating cost and stabilizing quality.
Finally, this micromixer can obtained mixing purpose when the operating condition at the rotation speed is 2500rpm, in 20 seconds for color distribution and ph determination.

並列關鍵字

micromixer ； biochip ； MEMS ； hot embossing

參考文獻

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