北市大都會區成年人代謝症候群之盛行率研究調查

Investigation of the Prevalence of Metabolic Syndrome of Adult People in Taipei, Taiwan

謝惠霓(Hui-Ni Hsieh)

指導教授 ： 許垤棋

大同大學/工程學院/生物工程學系所/碩士(2010年)

摘要

新陳代謝症候群可能會增加中老年人慢性疾病的產生。本研究目的為探討新陳代謝症候群的盛行率和各危險因子之間的相關性。
方法是以北市某聯合診所之健檢為樣本來源，收集自2009年4月至9月的有效樣本共714件作研究。診斷標準是依據美國國家膽固醇教育委員會Thired Report of NCEP (ATP III) 針對成年人的建議為準。統計方法是採用SPSS統計分析，利用獨立樣本t-檢定及卡方檢定來檢定組間的差異，及迴歸分析新陳代謝症候群和各相關危險因子間的關係。
研究結果714位受檢者中，男性255位 (佔35.7%)，女性459位 (佔64.3%)，平均年齡為48.37±9.52歲 (19歲起~78歲止)。整體新陳代謝症候群的盛行率為13.4%，其中男性為21.6%，女性8.9%，男女性新陳代謝症候群的盛行率在統計學上有顯著的差異性 (P<0.05)。經連續變數相關檢定，證明新陳代謝症候群和年齡、血壓、LDL-Cholesterol、BMI有顯著的正相關 (P<0.05)。卡方檢定結果顯示有煙癮的人和新陳代謝症候群有顯著的正相關 (P<0.05)，運動習慣和新陳代謝症候群有顯著的負相關 (P<0.05)，證明有長期運動習慣的人較不容易罹患新陳代謝症候群。使用邏輯斯回歸分析發現，證明血壓、BMI、血糖、三酸甘油脂和新陳代謝症候群呈顯著的正相關 (P<0.05)；而高密度膽固醇和新陳代謝症候群呈顯著的負相關 (P<0.05)。
本研究結論，證明男、女性新陳代謝症候群的盛行率有明顯的差異，且顯示出北市都會區整體新陳代謝症候群的盛行率比其它縣市的研究為偏低。

關鍵字

新陳代謝症候群 ； 高密度膽固醇 ； BMI ； 血糖 ； 三酸甘油脂

並列摘要

Metabolic syndrome will increase the possibility of chronic disease among the middle and old-aged people.To discuss the relevance of metabolic syndrome prevalence and each risk factors is the purpose of this study.
Methods: The measure used is taking the physical examination from a polyclinic in Taipei city as the source of samples which collected from April through September, 2009, altogether 714, to study. The diagnosis standard is based on the third Report of NECP (ATPIII) on adult’s suggestions. The statistical method adopts the SPSS statistical analysis which uses t-test of independent samples and Chi-Square Test to test the difference of groups, and the relationship between metabolic syndrome and each factor, also uses Regression analysis to analyze the relationship metabolic syndrome prevalence and each risk factors.
Results: The result indicates that there are 255 males (35.7%) and 459 females (64.3%), average age is 48.37±9.52 years old (19~78 years old), among the 714 patients. The prevalence of metabolic syndrome is 13.4% overall, for males and females is 21.6% and 8.9% respectively. Therefore, there is significant differentia of metabolic syndrome prevalence between males and females on statistics (P<0.05). It proves there is a significant positive relationship (P<0.05) among metabolic syndrome and age、blood pressure、LDL-Cholesterol and BMI, through correlation analysis. Chi-Square Test suggests that the correlation analysis between those addicted to smoking and metabolic syndrome shows a significant positive relationship (P<0.05). There is a significant negative relationship between those who have the habit of doing exercises and metabolic syndrome (P<0.05), so it indicates that the person who has the habit of doing exercises will not easy to get metabolic syndrome . Using Logistic Regression indicates that there is a significant positive relationship among blood pressure、BMI、Glucose、Triglyceride and metabolic syndrome (P<0.05). On the contrary, there is a significant negative relationship between metabolic syndrome and HDL-Cholesterol (P<0.05).
Conclusion: The result of this study indicates that the prevalence of metabolic syndrome exists significant difference between males and females，and indicates it lower in Taipei than in other counties.

並列關鍵字

HDL-Cholesterol ； BMI ； Blood glucose ； Metabolic syndrome ； Triglyceride

參考文獻

4.Chuang SY, Chen CH, Chou P.(2004) Prevalence of metabolic syndrome in a large health check-up population in Taiwan. J Chin Med Assoc.Dec;67(12):611-20.

30.張昌堯、郭雅音、陳佑寧、洪錦墩、陳榕生、廖朝財（2008） 南投地區中老年人代謝症候群盛行率. Journal of Biomedical & Laboratory Sciences, Volume 20.Number 3-4,2008;40-45.

31.張榮哲、黃麗卿、詹欣隆（2005） 某醫學中心體重過重員工罹患代謝症候群之危險因子研究 家醫研究2005;3:149-161.

1.Bondar RJ, Mead DC.(1974) Evaluation of glucose-6-phosphate dehydrogenase from Leuconostoc mesenteroides in the hexokinase method for determining glucose in serum. Clin Chem ;20:586-590.

2.Caraway WT, Watts NB.(1987) Carbohydrates. In:Tietz NW,ed.Fundamentals of Clinical Chemistry.3rd ed.philadelphia:WB Saunders:422-447.