本研究以自製的壓克力擬人型假體搭配TLD度量技術評量患者進行心導管診斷時之有效劑量值。現今臨床心導管診斷上往往需要很長的診斷和治療時間,加上整個過程中必須藉由X光機的透視輔助才得以完成,以至於病患接受長時間X光照射可能造成的輻射傷害,常常被醫生和病患所忽略。因此本論文希望藉由建立一個有效劑量的半經驗公式,期望對臨床病患的有效劑量值有一個更接近於真實的評估。本研究以熱發光劑量計佈點於自製的10、30、50、70和90公斤的壓克力擬人型假體中,分別照射70、140、210、280和420 秒後分析病患在診斷的過程中所接受到的有效劑量值,再將所量測的有效劑量值、假體BMI、照射時間以及皮膚劑量利用Mathematica數學軟體來得到半經驗公式並做更進一步的探討。在照射時間70、140、210、280和420 秒下,10公斤假體所量測之有效劑量值為343.56、625.96、880.32、1172.88、1850.01μSv;30公斤有效劑量值為546.77、859.62、1172.46、1485.31、2110.99μSv;50公斤有效劑量值為671.84、1232.98、1794.11、2355.25、3477.52μSv;70公斤有效劑量值為782.86、1257.89、1732.91、2207.95、3157.99μSv;90公斤有效劑量值為810.01、1386.84、1963.66、2540.5、3694.16μSv。有效劑量結果顯示病患接受心導管診斷而導致癌症或遺傳疾病之機率是很輕微的。
This study applied five indigenous PMMA phantoms to estimate the effective doses in cardiac angiography through TLD technique. The dose evaluation was investigated through the TLDs in 10, 30, 50, 70 and 90 kg PMMA phantom to simulate patient undergone interventional cardiac catheterization X-ray irradiation in reality. The phantom was exposed by Bi-plane X-ray facility for 70, 140, 210, 280 and 420 seconds, respectively to obtain either skin or effective dose according to the ICRP-60 report. The derived skin dose and effective dose were further reassembled into Mathematical program to derive several semi-empirical formulas in this work. Specifically, the derived effective doses for 10kg phantom were 343.56μSv、625.96μSv、880.32μSv、1172.88μSv and 1850.01μSv, 546.77μSv、859.62μSv、1172.46μSv、1485.31μSv and 2110.99μSv for 30 kg phantom; 71.84μSv、1232.98μSv、1794.11μSv、2355.25μSv、3477.52μSv for 50 kg phantom; 782.86μSv、1257.89μSv、1732.91μSv、2207.95μSv、3157.99μSv for 70 kg phantom and 810.01μSv、1386.84μSv、1963.66μSv、2540.5μSv、3694.16μSv for 90 kg phantom. The skin doses derived from various phantoms barely have correlation to the effective dose. Thus, any intension to connect the skin dose and effective dose became complicate and time wasting. Furthermore, the several derived semi-empirical formulas were proved to have high correlation and verified with the practical cases to solidify the potential application in future study.