Osseous Choristoma of the Tongue: Report of a Case and Review of the Literature

一位三十歲女性患者主訴於其右側舌基部背面，出現一無痛性堅硬腫塊，已一年餘。此腫塊經外科手術切除，組織病理檢查發現為一骨性迷離瘤。文獻回顧發現截至目前為止，英文文獻報告之骨性迷離瘤包括本病例在内共有57例。此腫瘤好犯女性，女性和男性患者之比例為2.8:1。臨床上此腫瘤最常發生於舌背後三分之一靠近輪廓狀舌乳頭或盲孔部位(75.4%)，其他好發部位包括舌背中三分之一(5.2%)，舌腹面(1.8%)，頰黏膜(14.0%)，臼齒後墊(1.8%)，下顎前齒槽骨舌側(1.8%)。組織學上，此病變主要為緻密層狀骨所組成，外被一薄層纖維結締組織，並覆蓋多層鳞狀上皮，骨性迷離瘤一般為良性腫瘤，以外科手術切除後，通常不會再發。文獻報告中，至今僅一例再發於頰黏膜，及一例發生於舌中段之惡性骨肉瘤。骨性迷離瘤之發生原因，雖有多種假說，但眞正之病因目前仍不十分明白。

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並列摘要

A 30-year-old female patient presented with a pedunculated hard mass on the right dorsal tongue base for one year. The lesion was excised and histopathologic examination showed an osseous choristoma. Review of the English-language literature revealed a total of 57 reported cases of osseous choristoma including the present case. The lesion occurred predominantly in females with a female to male ratio of 2.8: 1 and in the posterior dorsum of the tongue near the circumvallate papillae or the foramen cecum (75.4%). Other locations for the tumor occurrence included the middle third of the dorsum of the tongue (5.2%), ventral surface of the tongue (1.8%), buccal mucosa (14.0%), retromolar pad (1.8%), and lingual aspect of the alveolar process of the anterior mandible (1.8%). Microscopically, the lesion presents as a circumscribed mass of dense lamellar bone. It is usually treated by simple surgical removal and recurrence is rare. Only one recurrent case of the buccal mucosa and one malignant osseous tumor of the tongue have been reported in the literature. The etiology and pathogenesis of the tumor still remain obscure.

並列關鍵字

osseous choristoma ； osteoma ； tongue

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Osseous Choristoma of the Tongue: Report of a Case and Review of the Literature

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