A Comparative Study of the Clinical Course and Treatment of Maxillofacial Infection between Diabetic and Nondiabetic Patients

糖尿病患者與非糖尿病患者顎顏面感染的臨床過程及治療方法之比較研究

王東堯(Tung-Yiu Victor Wong) ； 陳宏安(Hung-An Chen) ； 張正宜(Cheng-Ye Chang) ； 吳達仁(Ta-Jen Wu) ； 韓良俊(Liang-Jiunn Hahn)

《中華民國口腔顎面外科學會雜誌》 4卷2期 (1993/09) Pp. 65-75

https://doi.org/10.7104/CJOMS.199309.0065

摘要

Patients with diabetes mellitus are said to be infection-prone. However, Whether this is true in maxillofacial region is not certain. Besides, how this disease affects the clinical courses of infections in this region is not fully understood. This study examined the differences between the DM Group patients and the non-DM Group patients who were hospitalized under the diagnosis of orofacial cellulites or abscess. Only patients of age 40 or older were included. Thirty-two patients were designated to DM Group in that they revealed diabetic history, or had fasting plasma glucose values over 200mg/dl at admission. Thirty-four patients with no history of diabetes and no plasma glucose level above 140mg/dl were categorized into non-DM Group. Comparing data of these two groups showed that significantly more DM Group patients were operated twice or more (p＜.001), more diabetic patients underwent general anesthesia procedures (P＜.01), more diabetics received extra-oral operations (p＜.001), and longer stay for the diabetics in hospital (p＜.05). It is noteworthy that more DM Group patients had extensive fascial space involvements (≧three spaces) (p＜.001). This result suggested that the diabetic patients were less capable of confining the infections, which might partly explain the complicated courses, and the prolonged hospitalizations despite more aggressive measures had been undertaken.

關鍵字

顎顏面感染 ； 糖尿病 ； 齒源性感染 ； 膿腫 ； 蜂窩組織炎

並列摘要

Patients with diabetes mellitus are said to be infection-prone. However, Whether this is true in maxillofacial region is not certain. Besides, how this disease affects the clinical courses of infections in this region is not fully understood. This study examined the differences between the DM Group patients and the non-DM Group patients who were hospitalized under the diagnosis of orofacial cellulites or abscess. Only patients of age 40 or older were included. Thirty-two patients were designated to DM Group in that they revealed diabetic history, or had fasting plasma glucose values over 200mg/dl at admission. Thirty-four patients with no history of diabetes and no plasma glucose level above 140mg/dl were categorized into non-DM Group. Comparing data of these two groups showed that significantly more DM Group patients were operated twice or more (p＜.001), more diabetic patients underwent general anesthesia procedures (P＜.01), more diabetics received extra-oral operations (p＜.001), and longer stay for the diabetics in hospital (p＜.05). It is noteworthy that more DM Group patients had extensive fascial space involvements (≧three spaces) (p＜.001). This result suggested that the diabetic patients were less capable of confining the infections, which might partly explain the complicated courses, and the prolonged hospitalizations despite more aggressive measures had been undertaken.

並列關鍵字

abscess ； cellulitis ； diabetes mellitus ； odontogenic infection ； maxillofacial infection