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起源於含齒性囊腫之鱗狀細胞癌-病例報告

Squamous Cell Carcinoma Arising in a Dentigerous CystA Case Report

摘要


鱗狀細胞癌是口内最常見的惡性腫瘤,但發生於含齒性囊腫内則十分罕見,依據Maxymiw及Wood在1991年所作的文獻回顧發現自1947年至1990年僅有十八個英文報告病例,以下顎臼齒區最常見。其臨床特徵為無痛性之腫脹,X光片呈現透射線區内包含一顆未萌出之牙齒,常被診斷為含齒性囊腫而施行囊腫剜除術。術後的組織切片檢查得知診斷後,需要再做廣泛性切除或加做頸部淋巴廓清術等處置。本病例為一個34歲男性,求診時主訴約兩週前發現上顎腭側左前方有一疼痛腫脹區,經X光檢查後發現有一未萌出贅生齒包含於一約3×2公分大小的透射線區内,初步診斷為含齒性囊腫,經剜除手術後,組織病理報告為鱗狀細胞癌,而再安排一次上顎廣泛切除手術。術後癒合情形良好,經四年追蹤檢查無再發現象,外觀及咀嚼功能藉補綴物而得以維持。這篇報告除了針對本病例的診斷與治療提出討論外,也回顧相關之文獻。

並列摘要


Suqamous Cell Carcinoma is the commonest malignant tumor in the mouth. But such case happens in dentigerous cyst is extremely rare. According to literature reviewed by Maxymiw and Wood in 1991, there were nothing but 18 cases written in English from 1947 to 1990, and occurred mostly in mandibular molar area. This was recognized as its clinical characteristics as a painless swelling. The X ray reveals an unerupted tooth enclosed in a radiolucent shadow. Often has it been diagnosed as a dentigerous cyst in the beginning. After performing cyst enucleation, it is found some conclusion by histopathologic examination. At that moment, wide excision or even radical neck dissection would be a plus. This case shows a 34 years old male had his chief complaints with a swelling in the left anterior palate, which caused pain for about 2 weeks. The X ray revealed an unerupted supernumerary tooth enclosed in a 3×2 cm radiolucent shadow. The tentative diagnosis was dentigerous cyst. After the cyst enucleation, the specimen was read as squamous cell carcinoma. Then a wide excision is performed, and post-operative healing seems to be fine. There's no recurrence found over the subsequent 4 years. The profile and masticatory function also remains by prosthesis. In addition to submitting further discussion for the diagnosis and treatment of the case by this report, it provides an overview and makes a reference to all related medical literature, too.

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