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非小細胞型肺癌之口腔轉移:病例報告

A Case Report of Non-small Cell Lung Cancer Metastasizing to Oral Cavity - A Case Report

摘要


根據文獻統計,口腔惡性腫瘤約有1%來自於其他部位原發病灶的轉移,而這些原發病灶多來自鎖骨以下,其中以肺部、乳房及腎臟的轉移最為常見。臨床表現因轉移部位不同而有所差異,但多以快速生長之牙齦腫塊或顎骨破壞呈現,並具有疼痛及程度不一之神經感覺異常。本病例求診時為右上及左下顎後牙區之快速增生牙齦腫塊,經入院詳察後診斷為非小細胞型肺癌轉移至口腔的病灶,本文將就轉移性口腔腫瘤之臨床表現、轉移機制及治療方式作一討論。

並列摘要


According to literature review, oral metastatic tumors account for approximately 1% of oral malignancy. Most of these primary malignancies arise from the locations below the clavicle. Lung, breast and kidney are the most frequent sites. Metastatic tumor may occur in the soft tissues or in the jawbones. Rapid growth gingival mass, destruction of jawbones, pain or paresthesia are the common clinical manifestations. In this article, we will present a case with initial chief complained of rapid growth mass over upper and lower gingivae. Non-small cell lung cancer with oral metastasis was diagnosed after comprehensive systemic review. Clinical presentation of oral metastatic tumor with its possible mechanism and treatment will be discussed in this article.

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