摘要
平滑肌肉瘤(Leiomyosarcoma)是罕見的惡性腫瘤，主要來自原始中胚層(primitive mesoderm)。源自中胚層的諸多原發惡性腫瘤具有多樣性的特徵，如組織學外觀，生物學行為，與解剖學位置；其對於藥物與放射線敏感度的反應也各不相同。另一方面，它們卻有相似的自然病史、形態學上的相似性、和有時候對治療的反應相似。而與上皮鱗狀細胞癌相比較，其因病例個數較少，也增加了研究上之困難度。本病例為一六歲之小男童，由於右頰側出現超過三個月之與痛性腫大而至門診求診，經過病理切片後診斷為來自中胚層之平滑肌肉瘤，因此安排入院於全身麻醉下作右頰側腫瘤之廣泛切除，並於術後在門診作密切之追蹤。由於口內之平滑肌肉瘤屬於罕見之口內惡性腫瘤，因此提出報告並作相關文獻之回顧。
並列摘要
Leimyosarcomas is a rare malignant tumor originally mainly from primitive mesoderm. Malignancy with primitive mesoderm origin could occur in any ages, but often in elder people. These malignant tumors with primitive mesoderm origin have various appearance and behavior in histological observation, but sometimes they present in similar progression and have some characteristics toward medical treatment in common. Difficulties in investigating of these tumors also results from their presentation as an uncommon disease. A 6-year-old child who suffered from painless swelling over right buccal cheek for about 3 months. He came to our OPD for help and incisional biopsy was performed and the result revealed spindle cell tumor with active mitoses. Leiomyosarcoma was diagnosed. Then he was arranged for wide excision under general anesthesia during admission. Final pathology report revealed grade 1 leiomyosarcoma. He was discharged under stable condition and followed up on OPD regularly. The purpose of this case report is to review the properties of leiomyosarcoma including its management and prognosis.