Ban Xia Xie Xin Decoction is used for treatment of epigastric fullness syndrome caused by misuse of Xiaochaihu decoction. Ban Xia Xie Xin Decoction is later widely used in various gastrointestinal and esophageal disease. Similar formulae like Sheng Jiang Xie Xin Decoction, Gan Cao Xie Xin Decoction, Huang lian Decoction that are modulated in herbs or dosage have effect in different disease. This is a good example to learn syndrome differentiation and treatment.