霍香正氣散對大腸癌術後與化療後之中醫體質量表（BCQ）問卷療效評估

背景：衛福部國民健康署民國102年癌症報告：結腸及直腸惡性腫瘤（以下統稱為大腸癌）發生率排名於男性第1位，女性第2位；當年總計有15,140位、平均每天有41人罹患大腸癌。大腸癌也高居十大癌症死因第3名，民國101年共有5,131人、平均每天有19人因大腸癌喪命。中醫已有數千年歷史，中醫藥是我國重要傳統文化之一，國人對於中醫接受度也很高。方法：本研究收集民國105年1月1日～106年12月31日期間，診斷大腸癌（C18、C19、C20）有接受西醫手術與化療。預計收案24位分成2組各12位，一組只接受西醫手術與化療後大腸癌病人另一組除了接受西醫手術與化療治療且有中醫藥（霍香正氣散）介入。以問卷方式評估病人是否因中醫藥（霍香正氣散）介入而改善其副作用。結果：在自己健康滿意度分數項目、身體狀態評估項目、對自己健康狀態項目、營養狀況項目：受試組都優於照組評比，體重變化分析：受試組與對照組平均下降比（3.3公斤：7.8公斤），兩組病人體重變化以Mantel-Haenszel Chi-Square進行分析是有統計學意義。結論：中醫體質量表（BCQ）問卷，體質類型分為三類型：陰虛、陽虛、痰濕淤滯。分別統計三項分數，三類型評比受試組是優於對照組是有統計學意義。

關鍵字

大腸癌；霍香正氣散；中醫體質量表

並列摘要

Background: Weifu Ministry of National Health 2013 Cancer Report: The incidence of colon and rectal malignancies (hereinafter collectively referred to as colorectal cancer) ranked first in men and second in women; in total, 15,140 in that year, an average of 41 people per day suffered from large intestine cancer., Colorectal cancer is also ranked third among the top ten cancer deaths. In the Republic of China, there were 5,131 people in 101, and an average of 19 people died every day due to colorectal cancer. Chinese medicine has existed for thousands of years. Chinese medicine is one of the important traditional cultures in our country. People in China are also very receptive to Chinese medicine. Method: This study collected the diagnosis of colorectal cancer (C18, C19, C20) from January 1, 2016 to December 31, 2017. It is estimated that 24 patients will be divided into two groups of 12, and one group will only receive Western medicine surgery and chemotherapy. The other group of patients with colorectal cancer will be treated with Western medicine and chemotherapy instead of traditional Chinese medicine (Huoxiang Zhengqi San) improve significantly. Result: The results of the questionnaire were better than the group evaluation in the self-health satisfaction score item, the physical state assessment item, the self-health status item, and the nutritional status item. The weight change analysis: the average decrease ratio of the test group and the control group (3.3 Kg: 7.8 kg), the changes in body weight of the two groups were statistically significant by Mantel-Haenszel Chi-Square. Conclusion: Chinese Medicine Body Constitution Questionnaire (BCQ) questionnaire, the physical types are divided into three types: yin deficiency, yang deficiency, phlegm and stasis. Three scores were counted separately, and the three types of evaluation were statistically significant compared with the control group.