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  • 期刊

顯影劑相關的急性腎損傷

Contrast-Associated Acute Kidney Injury

摘要


隨著顯影劑使用的增加,顯影劑相關的急性腎損傷(acute kidney injury, AKI)已成為AKI的重要原因。其機轉分為直接和間接的腎損傷。而顯影劑相關的AKI的風險受到患者本身和疾病等相關因素的影響。這當中慢性腎臟病(chronic kidney disease, CKD)是與患者相關的最強危險因素。AKI不但會加速CKD的惡化,更會增加病患死亡風險、出院之後的不良事件比率。目前預防及處置以減少顯影劑之使用量及靜脈內晶體溶液輸液治療為主。

並列摘要


With the expanding availability of angiography and contrast computed tomography, contrast-associated acute kidney injury (AKI) is one of the leading causes of AKI. Although not completely elucidated, direct and indirect effects are possible pathophysiological mechanisms. Pre-existing chronic kidney disease (CKD) is the strongest risk factor. Contrast-associated AKI is associated with prolonged hospitalization, increased short-term mortality, long-term mortality and accelerated progression of underlying CKD. Minimizing contrast and intravenous hydration via 0.9% saline is the mainstay of prevention.

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