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摘要


尿路結石是腎臟科常見的疾病,其中約90%為含鈣成分的結石,主要草酸鈣和磷酸鈣,尿酸結石約占腎結石的10%。慢性腹瀉、糖尿病、肥胖、代謝症候群都是尿酸結石的危險因子。導致尿酸結石的因素有尿量減少導致尿液濃縮、尿中排出的尿酸增多、尿液的pH < 5.5。無顯影劑的電腦斷層檢查被認為是最快速精準的診斷工具。鹼化尿液、增加水分攝取以及使用黃嘌呤氧化酶抑制劑(xanthine oxidase inhibitor),若無合併嚴重併發症,內科療法可以有效處理尿酸結石。

關鍵字

尿酸 結石 痛風 高尿酸血症

並列摘要


Urolithiasis is a common disease in Nephrology. Most of the stones are calcium-based stones composed of calcium phosphate or calcium oxalate, and uric acid nephrolithiasis accounts for about 10% of total stones. Chronic diarrhea, diabetes mellitus, obesity, and metabolic syndrome are risk factors of uric acid nephrolithiasis. The causes of uric acid stones including: decreased urine amount, hyperuricosuria, and urine pH less than 5.5. Computed tomography is the gold standard to diagnose urolithiasis. Urine alkalization, an increase of fluid intake, and the use of xanthine oxidase inhibitor could treat uric acid stones. Without severe complications, medical therapy is efficient in most patients with uric acid nephrolithiasis.

並列關鍵字

uric acid nephrolithiasis gout hyperuricemia

延伸閱讀


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  • 黃瓊雪(2012)。腫瘤溶解症候群與血液尿酸檢測台灣醫檢會報27(2),103-103。https://doi.org/10.6998/BTSLM.201206.0103
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  • Lin, M. T., Tsau, Y. K., Tsai, W. Y., Tsai, W. S., Lu, F. L., Hsiao, P. H., & Chen, C. H. (1999). Nephrocalcinosis in Childhood. Acta Paediatrica Sinica, 40(1), 27-30. https://doi.org/10.7097/APS.199902.0027

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