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低蛋白飲食會造成營養不良嗎?

Dose Low-Protein Diet Cause Malnutrition in Chronic Kidney Disease?

摘要


蛋白質代謝率提升及營養不良是慢性腎臟病(chronic kidney disease, CKD)患者常會面臨的議題。因此,合適的蛋白質攝取量是CKD的重要課題。由於高蛋白飲食會使腎絲球內壓力上升和腎絲球超濾率而導致腎功能損傷,目前研究多認為低蛋白飲食可減緩進展到腎衰竭的速度。另外,低蛋白飲食搭配合適的熱量攝取量被認為並不會造成太高營養不良、蛋白質能量耗損、或惡病質的風險。因此,低蛋白飲食加上足夠的熱量攝取或許可作為CKD合適的照護方式。

並列摘要


Elevated protein catabolism and malnutrition are common problems in the patients with chronic kidney disease (CKD). Therefore, the appropriate protein intake is a major topic in CKD. Because high protein diet may cause the glomerular damage by increased intraglomerular pressure and glomerular hyperfiltration, the current study recommends low protein diet may delay the progression to renal failure. According to the current studies, low protein diet with adequate calorie intake is with a minimal risk of malnutrition, protein-energy wasting, or cachexia. Therefore, low protein diet with adequate calorie intake may be an appropriate management of CKD.

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