Blood Glutathione Responses to Submaximal Exercise Females During the Follicular and Luteal Phases

運動對女性濾泡期與黃體期時血液中麩胱甘肽（GSH）反應的影響

鍾秀琴(Shiow-Chyn Chung)

《中原學報》 25卷2期 (1997/05) Pp. 39-44

https://doi.org/10.6358/JCYU.199705.0039

摘要

Glutathione (L-y-glutamyl-L-cysteinylgycine) is one of the major antioxidants in the body. The present study investigated blood glutathione responses to 75-80% of maximal oxygen consumption (VO2max) for 30 minutes in females during their follicular (F) and luteal phases (L). Resting estradiol level was 2.7 fold higher in luteal phase than in the follicular phase (F ＝ 54.4±12.0, L ＝ 147.2±25.5 pgml1, p＜0.002). Concentrations of blood total (TGSH) and reduced glutathione (GSH) decreased significantly after 75-80% of VO2max for 30 minutes in both phases of the menstrual cycle. Oxidized glutathione (GSSG) concentrations were similar before exercise (F = 0.19±0.01, L = 0.18±0.01 mM) and increased significantly after exercise in both phases of the menstrual cycle (F = 0.21±0.02, L = 0.23±0.01 mM). These results suggest that the menstrual cycle phase did not influence glutathione responses to exercise. This type of exercise did cause perturbation of blood glutathione status. It suggests that female subjects were under exercise-induced oxidative stress when exercising at 75-80% VO2max for 30 minutes.

關鍵字

麩胱甘肽 ； 運動引起之氣化壓力 ； 抗氧化劑 ； 最大有氧能力 ； 濾泡期 ； 黃體期

並列摘要

Glutathione (L-y-glutamyl-L-cysteinylgycine) is one of the major antioxidants in the body. The present study investigated blood glutathione responses to 75-80% of maximal oxygen consumption (VO2max) for 30 minutes in females during their follicular (F) and luteal phases (L). Resting estradiol level was 2.7 fold higher in luteal phase than in the follicular phase (F ＝ 54.4±12.0, L ＝ 147.2±25.5 pgml1, p＜0.002). Concentrations of blood total (TGSH) and reduced glutathione (GSH) decreased significantly after 75-80% of VO2max for 30 minutes in both phases of the menstrual cycle. Oxidized glutathione (GSSG) concentrations were similar before exercise (F = 0.19±0.01, L = 0.18±0.01 mM) and increased significantly after exercise in both phases of the menstrual cycle (F = 0.21±0.02, L = 0.23±0.01 mM). These results suggest that the menstrual cycle phase did not influence glutathione responses to exercise. This type of exercise did cause perturbation of blood glutathione status. It suggests that female subjects were under exercise-induced oxidative stress when exercising at 75-80% VO2max for 30 minutes.

並列關鍵字

glutathione ； exercise-induced oxidative stress ； antioxidant ； VO2max ； follicular phase ； luteal phase