”Bioindustry,” a norm of the knowledge-based economy, to create and operate the industry to obtain a successful advantage has been becoming an endeavoring guideline for the knowledge-industry and the national innovation system in future. In this research, the conception of the centralized tendency of ”Operational Key Success Factors [39]” has been taken to extract and discuss hopefully the successful key-factors through the reference-analyzing approach with qualitative-quantitative crossing analysises. For developing Taiwanese bioindustry, according to conclusion and discoveries from this research, offered relative and directional; and feasible proposals with measures to formed complete sets.