A 73-year-old patient with advancer stage prostate adenocarcinoma required several hospitalizations because of metastatic bone disease causing persistent cancer pain. His wife, also the key care-provider, harbored persecutory delusion resulting from long-term domestic violence. The patient’ s psychological distress and physical derangement got alleviated after hospice referral and specialists’ intervention. His wife can continuously receive psychiatric treatment and resumed to her daily activity as well after the patient pass away. Both his family and the death had peace of mind eventually.